FB2026_02 , released June 18, 2026
Allele: Dmel\morgue457
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General Information
Symbol
Dmel\morgue457
Species
D. melanogaster
Name
FlyBase ID
FBal0264700
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Nature of the Allele
Allele class
Cytology
Description

Imprecise excision of the progenitor insertion, resulting in a 595bp deletion that removes part of the morgue gene (the coding region up to Asp145 is deleted).

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Comment:

595 bp deletion resulting from the imprecise excision of P{SUPor-P}Elp3KG02386, which extends from the insertion site up to amino acid residue D145 of morgue. Boundaries approximate.

Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygous flies are somewhat lethargic.

One or both of the anterior spiracles of the pupal case fail to evert and extend in 13% of homozygotes. 10.2% of eclosed homozygous adults show malformations in the tergite plates on the dorsal abdomen.

Stage 16 mutant embryos have aberrant midline glial cytoplasmic processes that are not well separated and often extend across inter-ganglia borders.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement
Reference

morgue[+]/morgue457 is a suppressor of visible phenotype of hidGMR.PG

morgue[+]/morgue457 is a suppressor of increased cell death phenotype of hidGMR.PG

Phenotype Manifest In
Suppressor of
Statement
Reference

morgue[+]/morgue457 is a suppressor of eye phenotype of hidGMR.PG

Additional Comments
Genetic Interactions
Statement
Reference

The ectopic eye death seen in flies carrying WGMR.PG is dominantly suppressed by by morgue457.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (1)