UASt regulatory sequences drive expression of a soluble extracellular fragment of the 500aa isoform of PGRP-LC (amino acids 312-500). The construct is tagged at the C-terminal end with Tag:FLAG.
abnormal immune response, with Scer\GAL4Cg.PA
abnormal immune response, with Scer\GAL4Hml.PG
abnormal immune response, with Scer\GAL4yolk
Expression of PGRP-LCa-V.Scer\UAS.T:Zzzz\FLAG under the control of either Scer\GAL4Cg.PA, Scer\GAL4Hml.PG or Scer\GAL4yolk does not induce IMD pathway activation in the absence of bacterial infection.