FlyBase Allele Report: Scer\GAL4[yolk]

General Information

Symbol

Scer\GAL4^yolk

Species

S. cerevisiae

Name

FlyBase ID

FBal0126479

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{yolk-GAL4}

Also Known As

yolk-Gal4, YP1-Gal4, yolkGAL4, P{GAL4-YP₁.JMR}

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Reichhart, 2001.9.14, Vidal et al., 2001)

Progenitor genotype

Carried in construct

P{yolk-GAL4}

Cytology

Description

Promoter sequences from between the Yp1 and Yp2 genomic loci drive expression of exon 1 of Yp1 fused with sequence encoding a GAL4 driver.

(Reichhart, 2001.9.14)

Allele components

Component

Use(s)

Regulatory region(s)

Yp1_yolk-Gal4

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage | female

adult fat body

(Reichhart, 2001.9.14)

Additional Information

Statement

Reference

Drives expression in the adult female fat body.

(FlyBase Curators, 2017)

Marker for

Reflects expression of

Yp1

(Bloomington Drosophila Stock Center, 2017)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal circadian rhythm, with Clk^DN.UAS

(Xu et al., 2008)

abnormal feeding behavior | adult stage, with Mondo^RNAi.Sym.UAS

(Sassu et al., 2012)

abnormal immune response, with Cap-D3^GD913

(Longworth et al., 2012)

abnormal immune response, with casp^UAS.Tag:MYC

(Kim et al., 2006)

abnormal immune response, with Fadd^RNAi.UAS

(Leulier et al., 2002)

abnormal immune response, with Fadd^RNAi.UASp.SN

(Naitza et al., 2002)

abnormal immune response, with HIV-1\Vpu^UAS.cLa

(Leulier et al., 2003)

abnormal immune response, with imd^KK109863

(Longworth et al., 2012)

abnormal immune response, with PGRP-LC^a.UAS.EGFP

(Schmidt et al., 2008)

abnormal immune response, with PGRP-LC^{a.UAS.Tag:FLAG}

(Schmidt et al., 2008)

abnormal immune response, with PGRP-LC^{a-III.UAS.Tag:FLAG}

(Schmidt et al., 2008)

abnormal immune response, with PGRP-LC^{a-V.UAS.Tag:FLAG}

(Schmidt et al., 2008)

abnormal immune response, with PGRP-LC^{I.UAS.Tag:FLAG}

(Schmidt et al., 2008)

abnormal immune response, with PGRP-LC^{II.UAS.Tag:FLAG}

(Schmidt et al., 2008)

abnormal immune response, with PGRP-LC^x.UAS.EGFP

(Schmidt et al., 2008)

abnormal immune response, with PGRP-LC^{x.UAS.Tag:FLAG}

(Schmidt et al., 2008)

abnormal immune response, with PGRP-LC^{x-IV.UAS.Tag:FLAG}

(Schmidt et al., 2008)

abnormal immune response, with PGRP-LC^{x-VI.UAS.Tag:FLAG}

(Schmidt et al., 2008)

abnormal immune response, with PGRP-LF^UAS.GFP

(Maillet et al., 2008)

abnormal immune response, with Rbf^GD4484

(Longworth et al., 2012)

abnormal immune response, with Sting^GD1905

(Segrist et al., 2024)

abnormal immune response, with Tak1^NIG.1388R

(Leulier et al., 2002)

abnormal immune response | adult stage, with hpo^GD1570

(Liu et al., 2016)

abnormal immune response | adult stage, with Mtr4^GD11229

(Molleston et al., 2016)

abnormal immune response | adult stage, with PGRP-LC^A.EC.UAS

(Maillet et al., 2008)

abnormal immune response | adult stage, with PGRP-LC^A.TM+EC.UAS

(Maillet et al., 2008)

abnormal immune response | adult stage, with Rrp4^KK108526

(Molleston et al., 2016)

abnormal immune response | adult stage, with Rrp6^HMS00118

(Molleston et al., 2016)

abnormal immune response | adult stage, with spz^KK112908

(Liu et al., 2016)

abnormal immune response | adult stage, with Tl^KK103505

(Liu et al., 2016)

abnormal immune response | adult stage, with wts^KK101055

(Liu et al., 2016)

abnormal immune response | adult stage, with yki^UAS.cHa

(Liu et al., 2016)

abnormal immune response | adult stage, with Zcchc7^KK103416

(Molleston et al., 2016)

abnormal immune response | female | semidominant

(Keith et al., 2026)

abnormal oxidative stress response, with Mrp4^EP3177

(Huang et al., 2014)

abnormal starvation stress response, with p53^GD4483

(Barrio et al., 2014)

abnormal starvation stress response, with p53^GUS.PB

(Barrio et al., 2014)

abnormal starvation stress response, with p53^H159N.UAS.Ex

(Barrio et al., 2014)

abnormal starvation stress response | adult stage, with Tnpo-SR^JF02010

(Nagle et al., 2022)

abnormal starvation stress response | semidominant

(Keith et al., 2026)

decreased cell number | adult stage, with Tnpo-SR^JF02010

(Nagle et al., 2022)

decreased fecundity | female

(Keith et al., 2026)

decreased rate of feeding behavior | adult stage, with Srpk79D^HMC04154

(Mercier et al., 2023)

decreased rate of feeding behavior | adult stage, with SRPK^HMS04491

(Mercier et al., 2023)

decreased rate of feeding behavior | adult stage, with Tnpo-SR^JF02010

(Nagle et al., 2022)

decreased size | female limited

(Keith et al., 2026)

fertile, with FHV\A^RNA1.UAS

(Galiana-Arnoux et al., 2006)

fertile, with FHV\B2^RNA1.UAS

(Galiana-Arnoux et al., 2006)

fertile, with FHV\gp1^RNA2.UAS

(Galiana-Arnoux et al., 2006)

increased body size | adult stage, with Tnpo-SR^JF02010

(Nagle et al., 2022)

increased mortality | adult stage | conditional, with Sting^GD1905

(Segrist et al., 2024)

increased mortality | semidominant

(Keith et al., 2026)

lethal - all die before end of larval stage, with Mmp1^F1.C93A.UAS

(Schmidt et al., 2011)

partially lethal - majority die, with Mmp2^UAS.cPa

(Schmidt et al., 2011)

partially lethal - majority live, with nec^1.UAS

(Green et al., 2003)

partially lethal - majority live, with nec^9.UAS

(Green et al., 2003)

partially lethal - majority live, with nec^SF.UAS

(Green et al., 2003)

partially lethal - majority live, with nec^UAS.cLa

(Green et al., 2003)

short lived, with nec^1.UAS

(Green et al., 2003)

short lived, with nec^9.UAS

(Green et al., 2003)

short lived, with nec^SF.UAS

(Green et al., 2003)

short lived, with nec^UAS.cLa

(Green et al., 2003)

some die during larval stage, with Mmp1^F1.C93A.UAS

(Schmidt et al., 2011)

sterile, with Mmp2^UAS.cPa

(Schmidt et al., 2011)

viable, with 4Csp2^UAS.cSa

(Sabatier et al., 2003)

viable, with FHV\A^RNA1.UAS

(Galiana-Arnoux et al., 2006)

viable, with FHV\B2^RNA1.UAS

(Galiana-Arnoux et al., 2006)

viable, with FHV\gp1^RNA2.UAS

(Galiana-Arnoux et al., 2006)

viable, with teq^{UAS.Tag:SS(Drs)}

(Munier et al., 2004)

visible, with Tak1^UAS.cMa

(Stronach et al., 2014)

visible | adult stage, with Tnpo-SR^JF02010

(Nagle et al., 2022)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^yolk has decreased fecundity | female phenotype, enhanceable by BacA\p35^UAS.cHa

(Keith et al., 2026)

NOT Enhanced by

Statement

Reference

Scer\GAL4^yolk has increased mortality | semidominant phenotype, non-enhanceable by BacA\p35^UAS.cHa

(Keith et al., 2026)

Scer\GAL4^yolk has abnormal immune response | semidominant | female phenotype, non-enhanceable by BacA\p35^UAS.cHa

(Keith et al., 2026)

NOT suppressed by

Statement

Reference

Scer\GAL4^yolk has increased mortality | semidominant phenotype, non-suppressible by BacA\p35^UAS.cHa

(Keith et al., 2026)

Scer\GAL4^yolk has abnormal immune response | semidominant | female phenotype, non-suppressible by BacA\p35^UAS.cHa

(Keith et al., 2026)

NOT Suppressor of

Statement

Reference

casp^UAS.Tag:MYC/Scer\GAL4^yolk is a non-suppressor of abnormal immune response phenotype of Tl³

(Kim et al., 2006)

Hayan^UAS.cLa/Scer\GAL4^yolk is a non-suppressor of abnormal immune response phenotype of psh^unspecified

(Ligoxygakis et al., 2002)

Scer\GAL4^yolk/ea^Δ.UAS is a non-suppressor of abnormal immune response phenotype of psh^unspecified

(Ligoxygakis et al., 2002)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Scer\GAL4^yolk has adult abdominal fat mass phenotype, non-enhanceable by BacA\p35^UAS.cHa

(Keith et al., 2026)

Scer\GAL4^yolk has adult fat body phenotype, non-enhanceable by BacA\p35^UAS.cHa

(Keith et al., 2026)

NOT suppressed by

Statement

Reference

Scer\GAL4^yolk has adult abdominal fat mass phenotype, non-suppressible by BacA\p35^UAS.cHa

(Keith et al., 2026)

Scer\GAL4^yolk has adult fat body phenotype, non-suppressible by BacA\p35^UAS.cHa

(Keith et al., 2026)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Scer\GAL4^yolk is rescued by Scer\GAL4^{RNAi.2.UAS.VALIUM20}, Scer\GAL4^yolk

(Keith et al., 2026)

Rescues

Scer\GAL4^{RNAi.2.UAS.VALIUM20}, Scer\GAL4^yolk rescues Scer\GAL4^yolk

(Keith et al., 2026)

Scer\GAL4^yolk/PGRP-LC^A.TM+IC.UAS rescues PGRP-LC^ΔE

(Maillet et al., 2008)

casp^UAS.Tag:MYC/Scer\GAL4^yolk rescues casp^P1

(Kim et al., 2006)

psh^UAS.cLa/Scer\GAL4^yolk rescues psh^unspecified

(Ligoxygakis et al., 2002)

Fails to rescue

Scer\GAL4^yolk/PGRP-LC^A.EC.UAS fails to rescue PGRP-LC^ΔE

(Maillet et al., 2008)

Scer\GAL4^yolk/PGRP-LC^A.TM+EC.UAS fails to rescue PGRP-LC^ΔE

(Maillet et al., 2008)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

58814

y¹ w^*; P{yolk-GAL4}2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Scer\GAL4^yolk

Name Synonyms

Secondary FlyBase IDs

References (78)

Report Sections

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