FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\caspP1
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General Information
Symbol
Dmel\caspP1
Species
D. melanogaster
Name
FlyBase ID
FBal0197501
Feature type
allele
Associated gene
Dmel\casp
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Kim et al., 2006)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      caspP1 mutants exhibit a high rate of melanisation, found in 15% of larvae, 14% of pupae, and 17.5% of adults. This melanisation is conspicuous around internal organs such as the gut and fat body.

      caspP1 flies exhibit a much higher survival rate compared to wildtype, when pricked with a needle dipped in a concentrated solution of gram-negative Esherichia coli or Erwinia carotovora.

      caspP1/Df(2R)ED2457 transallelic mutants display phenotypes identical to those of caspP1 homozygotes.

      (Kim et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      caspP1 is rescued by caspUAS.Tag:MYC/Scer\GAL4da.G32

      (Kim et al., 2006)

      caspP1 is rescued by caspUAS.Tag:MYC/Scer\GAL4yolk

      (Kim et al., 2006)
      Comments

      Expression of caspScer\UAS.T:Hsap\MYC, under the control of Scer\GAL4da.G32 or Scer\GAL4yolk rescues the caspP1 phenotype.

      (Kim et al., 2006)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      caspP1
      (Kim et al., 2006)
      Name Synonyms
      casparP1
      (Kim et al., 2006)
      Secondary FlyBase IDs
        References (1)