FB2026_02 , released June 18, 2026
Allele: Dmel\teqUAS.Tag:SS(Drs)
Open Close
General Information
Symbol
Dmel\teqUAS.Tag:SS(Drs)
Species
D. melanogaster
Name
FlyBase ID
FBal0175778
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Progenitor genotype
Carried in construct
Cytology
Description

UASt regulatory sequences drive expression of the serine protease domain of teq (amino acids 1181-1426) fused at the N-terminal end with the Drs signal peptide (Tag:SS(Drs)). The teq sequence contains the amino acid replacement C1295S (the Cys residue is required for the protease/protease prodomain disulfide bond). Encodes an autoactivated form of teq.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Overexpression of TequilaScer\UAS.T:Drs, whether driven by Scer\GAL4da.G32 or Scer\GAL4yolk, does not affect the survival rate of flies when challenged with E.coli, M.luteus or B.bassiana. Additionally, the processes of melanization and coagulation are unaffected.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
TequilaScer\UAS.T:Drs
TequilaScer\UAS.T:SS-Drs
teqScer\UAS.T:SS-Drs
teqUAS.Tag:SS(Drs)
Name Synonyms
Secondary FlyBase IDs
    References (1)