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General Information
Symbol
Dmel\spzKK112908
Species
D. melanogaster
Name
FlyBase ID
FBal0238478
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
exacerbates  cancer
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of spzKK112908 driven in the fat body of male flies by Scer\GAL4r4 (or driven by Scer\GAL4yolk in female fat bodies) significantly decreases survival of flies in response to Gram-positive bacteria (Staphylococcus aureus or Enterococcus faecalis) and a fungus (Aspergillus fumigatus), compared to controls. Bacterial load (measured as colony forming units 24hr post infection) of S. aureus significantly increases in adult flies, compared to controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhancer of
Statement
Reference
Other
Additional Comments
Genetic Interactions
Statement
Reference

The apoptosis observed in dlg1A40.2 mutant wing disc tumors is virtually abrogated by the expression of spzKK112908 under the control of either Scer\GAL4He.PZ or Scer\GAL4Hml.Δ.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
spzKK112908
Name Synonyms
Secondary FlyBase IDs
    References (5)