FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\DroncS130A.UAS.Tag:FLAG
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General Information
Symbol
Dmel\DroncS130A.UAS.Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0264882
Feature type
allele
Associated gene
Dmel\Dronc
Associated Insertion(s)
Carried in Construct
P{UAS-Dronc.S130A.FLAG}
Key Links
Transgenic product class
missense_variant
(Yang et al., 2010)
polypeptide_post_translational_processing_variant
(Yang et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Yang et al., 2010)
polypeptide_post_translational_processing_variant
(Yang et al., 2010)
Mutagen
in vitro construct
(Yang et al., 2010)
Progenitor genotype
Carried in construct
P{UAS-Dronc.S130A.FLAG}
Cytology
Description

UAS regulatory sequences drive expression of a non-phosphorylatable form of Dronc (contains the amino acid replacement S130A) which is tagged with Tag:FLAG.

(Yang et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Dronc
Tagged with
Tag:FLAG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Scer\GAL4GMR.PF-driven overexpression of NcS130A.Scer\UAS.T:Zzzz\FLAG results in a rough eye phenotype.

      Expression of NcS130A.Scer\UAS.T:Zzzz\FLAG pan-neuronally under the control of Scer\GAL4elav-C155 results in severe wing expansion defects.

      (Yang et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Enhanced by
      Statement
      Reference

      DroncS130A.UAS.Tag:FLAG, Scer\GAL4elav-C155 has wing phenotype, non-enhanceable by MenKK107809, Scer\GAL4elav-C155

      (Yang et al., 2010)
      NOT suppressed by
      Statement
      Reference

      DroncS130A.UAS.Tag:FLAG, Scer\GAL4elav-C155 has wing phenotype, non-suppressible by MenKK107809, Scer\GAL4elav-C155

      (Yang et al., 2010)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Down-regulation of Men through expression of MenKK107809 under the control of Scer\GAL4elav-C155 has no effect on the severe wing expansion defects seen upon expression of NcS130A.Scer\UAS.T:Zzzz\FLAG.

      (Yang et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      DroncS130A.Scer\UAS.T:Zzzz\FLAG
      DroncS130A.UAS.Tag:FLAG
      NcS130A.Scer\UAS.T:Zzzz\FLAG
      NcS130A.Scer\UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (2)