FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\tauMI03440
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General Information
Symbol
Dmel\tauMI03440
Species
D. melanogaster
Name
FlyBase ID
FBal0265468
Feature type
allele
Associated gene
Dmel\tau
Associated Insertion(s)
Mi{MIC}tauMI03440
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    Mi{MIC}tauMI03440
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    Mi{MIC}
    Also carries
    attP
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 1 )
        Disease
        Evidence
        References
        model of  tauopathy
        CEA
        (Papanikolopoulou et al., 2019)
        Modifiers Based on Experimental Evidence ( 1 )
        Disease
        Interaction
        References
        exacerbates  tauopathy
        modeled by Hsap\MAPTUAS.cWa
        (Feuillette et al., 2020)
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        tauMI03440 mutant adults have significantly increased aversive olfactory 24 h memory following spaced, but not massed, training, with no effect on 3 min memory, compared to controls; they have normal naive avoidance of electric shocks, but have a significant failure to habituate to shocks, compared to controls.

        (Papanikolopoulou et al., 2019)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Enhancer of
        Statement
        Reference

        tauMI03440/tau[+] is an enhancer of visible | adult stage phenotype of Hsap\MAPTUAS.cWa, Scer\GAL4GMR.PF

        (Feuillette et al., 2020)
        Phenotype Manifest In
        Enhancer of
        Statement
        Reference

        tauMI03440/tau[+] is an enhancer of eye phenotype of Hsap\MAPTUAS.cWa, Scer\GAL4GMR.PF

        (Feuillette et al., 2020)
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        tauMI03440
        (Feuillette et al., 2020, Bellen, 2012.1.3)
        tauMI
        (Papanikolopoulou et al., 2019)
        Name Synonyms
        Secondary FlyBase IDs
          References (4)