FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Cyp6a17Δ173
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General Information
Symbol
Dmel\Cyp6a17Δ173
Species
D. melanogaster
Name
FlyBase ID
FBal0266058
Feature type
allele
Associated gene
Dmel\Cyp6a17
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Kang et al., 2011)
Mutagen
P-element activity
(Kang et al., 2011)
Progenitor genotype
P{SUPor-P}Cyp6a17KG04448
(Kang et al., 2011)
Cytology
Description

Imprecise excision of the progenitor insertion, resulting in a 1096bp deletion that extends from +133 to +1236 relative to the translation start site.

(Kang et al., 2011)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutant flies show a reduced avoidance index for low temperature in a temperature preference behaviour assay.

      (Kang et al., 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Cyp6a17Δ173 is rescued by Scer\GAL4Cyp6a17.MB/Cyp6a17UAS.cKa

      (Kang et al., 2011)

      Cyp6a17Δ173 is rescued by Scer\GAL4Mef2.247/Cyp6a17UAS.cKa

      (Kang et al., 2011)

      Cyp6a17Δ173 is rescued by Cyp6a17+t4.2

      (Kang et al., 2011)
      Comments

      Cyp6a17+t4.2 rescues the abnormal temperature preference behaviour of Cyp6a17Δ173 flies.

      Expression of Cyp6a17Scer\UAS.cKa under the control of either Scer\GAL4Mef2.247 or Scer\GAL4Cyp6a17.MB rescues the abnormal temperature preference behaviour of Cyp6a17Δ173 flies.

      (Kang et al., 2011)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Cyp6a17Δ173
      cyp6a17Δ173
      (Kang et al., 2011)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)