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General Information
Symbol
Dmel\atlHMS01627
Species
D. melanogaster
Name
FlyBase ID
FBal0266534
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of a short inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The expression of atlHMS01627 under the control of Scer\GAL4221 in larval ddaE neurons leads to defects in axon regeneration, shown by a significant decrease in axon length and by a lower recruitment of endoplasmic reticulum to the axon tip (marked by fluorescent Rtnl1), but not in dendrite regeneration, shown by a similar dendrite number, at 96h after laser-induced severance, as compared to controls. These neuron show an apparently normal early response to injury, since the pool of growing microtubules (identified as fluorescent EB1 comets) shows the expected increase in number and the expected reversal of polarity at 24h after laser-induced severance, as compared to controls. Uninjured atlHMS01627-expressing neurons shown no obvious endoplasmic reticulum defects, as compared to controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
atlHMS01627
Name Synonyms
Secondary FlyBase IDs
    References (3)