FB2026_02 , released June 18, 2026
Allele: Dmel\GnmtMI04290
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General Information
Symbol
Dmel\GnmtMI04290
Species
D. melanogaster
Name
FlyBase ID
FBal0266642
Feature type
allele
Associated gene
Dmel\Gnmt
Associated Insertion(s)
Mi{MIC}GnmtMI04290
Carried in Construct
Also Known As
gnmtMi
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
    Nature of the Allele
    Allele class

    amorphic allele - molecular evidence

    (Obata et al., 2014)
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    Mi{MIC}GnmtMI04290
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    Mi{MIC}
    Also carries
    attP
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        GnmtMI04290 mutant flies do not show the increase in lifespan in response seen in wild type flies in response to dietary restriction.

        (Obata and Miura, 2015)

        GnmtMI04290 flies are hypersusceptible to starvation stress compared to wild type.

        (Obata et al., 2014)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Enhanced by
        Statement
        Reference

        GnmtMI04290 has abnormal starvation stress response phenotype, enhanceable by DarkCD4

        (Obata et al., 2014)
        Enhancer of
        Statement
        Reference

        GnmtMI04290 is an enhancer of abnormal starvation stress response phenotype of DarkCD4

        (Obata et al., 2014)
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        ArkCD4 GnmtMI04290 double mutants show a starvation stress phenotype that is more severe than in either single mutant.

        (Obata et al., 2014)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (3)
        Reported As
        Symbol Synonym
        CG6188MI04290
        (Bellen, 2012.2.2)
        GnmtMI04290
        gnmtMi
        (Kashio et al., 2016, Obata et al., 2014)
        Name Synonyms
        Secondary FlyBase IDs
          References (4)