FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Sp1L.UAS
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General Information
Symbol
Dmel\Sp1L.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0267375
Feature type
allele
Associated gene
Dmel\Sp1
Associated Insertion(s)
Carried in Construct
P{UAS-Sp1.L}
Key Links
Transgenic product class
wild_type
(Estella and Mann, 2010)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Estella and Mann, 2010)
Mutagen
in vitro construct
(Estella and Mann, 2010)
Progenitor genotype
Carried in construct
P{UAS-Sp1.L}
Cytology
Description

UASt regulatory sequences drive expression of the Sp1-RD isoform of Sp1.

(Estella and Mann, 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Sp1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Sp1L.Scer\UAS under the control of Scer\GAL4dpp.blk1 produces wing to leg transformations in the adult appendage.

      (Estella and Mann, 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4Tub.PU/Sp1L.UAS partially rescues Df(1)btd-Sp1

      (Estella and Mann, 2010)

      Scer\GAL4Dll-em212/Sp1L.UAS partially rescues Df(1)btd-Sp1

      (Estella and Mann, 2010)
      Comments

      Expression of Sp1L.Scer\UAS (generated using the MARCM system under the control of Scer\GAL4tub.PU) partially rescues the growth defects seen in Df(1)btd-Sp1 leg disc clones in second instar larvae.

      Expression of Sp1L.Scer\UAS partially rescues the growth defects seen in Df(1)btd-Sp1 mutant leg clones generated in a minute background during embryogenesis using Scer\FLP1Scer\UAS.cUa under the control of Scer\GAL4Dll-em212.

      (Estella and Mann, 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Sp1L.Scer\UAS
      Sp1L.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)