FB2026_02 , released June 18, 2026
Allele: Dmel\Eip93F4
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General Information
Symbol
Dmel\Eip93F4
Species
D. melanogaster
Name
FlyBase ID
FBal0267795
Feature type
allele
Associated gene
Dmel\Eip93F
Associated Insertion(s)
Carried in Construct
Also Known As
E934
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    Amino acid replacement: ?360term.

    (Mou et al., 2012)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    point_mutation
    3R:22,004,084..22,004,084 [+]
    Nucleotide change:

    C22004084T

    Amino acid change:

    Q360term | Eip93F-PA; Q383term | Eip93F-PB; Q360term | Eip93F-PC

    Reported amino acid change:

    ?360term

    Comment:

    Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change. The nonsense mutations were reported with respect to isoform Eip93F-PA.

    (Mou et al., 2012)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Eip93F4/Df(3R)Exel6188 mutants show slightly increased persistence of larval salivary gland in the pupa.

        (Duncan et al., 2017)

        Homozygotes die just before emergence of the adult and show numerous defects affecting the eyes, antennae, palps, labellum, wings, legs and abdomen. Wing veins are absent, most antennal sensilla are absent, abdominal tergites show mirror symmetry and bracts are absent from the leg.

        Homozygous bract cells are never seen in somatic clones induced in the leg, while homozygous bristles are recovered.

        (Mou et al., 2012)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Fails to complement

        Eip93FVno

        (Mou et al., 2012)

        Eip93Fry93

        (Mou et al., 2012)
        Comments

        The Eip93FΔ1 allele fails to complement Eip93F4 from the 'E93[4-6]' complementation group.

        (Duncan et al., 2017)
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        E934
        (Lam et al., 2022, Mika et al., 2021, Duncan et al., 2017, Uyehara et al., 2017, Mou et al., 2012)
        Eip93F4
        Name Synonyms
        Secondary FlyBase IDs
          References (5)