FB2026_02 , released June 18, 2026
Allele: Dmel\Apc2ΔArmRepeats.EGFP
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General Information
Symbol
Dmel\Apc2ΔArmRepeats.EGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0267814
Feature type
allele
Associated gene
Dmel\Apc2
Associated Insertion(s)
Carried in Construct
PBac{Apc2-EGFP.ΔArmRepeats}
Key Links
Transgenic product class
inframe_deletion
(Roberts et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Roberts et al., 2012)
Mutagen
in vitro construct
(Roberts et al., 2012)
Progenitor genotype
Carried in construct
PBac{Apc2-EGFP.ΔArmRepeats}
Cytology
Description

EGFP is fused to a mutant form of Apc2 lacking the Arm repeats but retaining the 15 and 20 amino acid repeats and SAMP repeats (amino acids 466-1067). Expression is driven using the Apc2 ATG codon and endogenous promoter.

(Roberts et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
Apc2
Encoded product / tool
Apc2
Tagged with
EGFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of Apc2ΔArmRepeats.T:Avic\GFP-EGFP provides a very weak rescue of the anterior fate loss seen in Apc2g10 ApcQ8 maternal/zygotic mutant embryos.

      (Roberts et al., 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Apc2ΔArmRepeats.EGFP partially rescues Apc2g10

      (Roberts et al., 2012)
      Comments

      Expression of Apc2ΔArmRepeats.T:Avic\GFP-EGFP partially rescues the loss of anterior fates seen in maternal/zygotic Apc2g10 mutant embryos. Denticle belts are largely restored to the cuticle.

      (Roberts et al., 2012)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Apc2ΔArmRepeats.EGFP
      Apc2ΔArmRepeats.T:Avic\GFP-EGFP
      Name Synonyms
      Secondary FlyBase IDs
        References (2)