FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\CapaRRNAi.UAS
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General Information
Symbol
Dmel\CapaRRNAi.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0268240
Feature type
allele
Associated gene
Dmel\CapaR
Associated Insertion(s)
Carried in Construct
P{UAS-CapaR.RNAi}
Also Known As
UAS-capaR RNAi
Key Links
Transgenic product class
RNAi_reagent
(Terhzaz et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Terhzaz et al., 2012)
Mutagen
in vitro construct
(Terhzaz et al., 2012)
Progenitor genotype
Carried in construct
P{UAS-CapaR.RNAi}
Cytology
Description

UAS regulatory sequences drive expression of an inverted repeat of a 615 base pair fragment of CapaR.

(Terhzaz et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
CapaR
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Adulthood-only expression of CapaRdsRNA.UAS under the control of Scer\GAL4how-24B (together with Gal80[ts] for the temporal control of expression) leads to decreased walking activity; individuals present a delay in gut transit, as well as fewer, smaller, and more concentrated fecal deposits; the feeding time is decreased and food consumption is decreased.

      The expression of CapaRdsRNA.UAS under the control of Scer\GAL4GMR21E06 leads to to decreased adult walking activity.

      The expression of CapaRdsRNA.UAS under the control of Scer\GAL4Uro.PT leads to fewer, but not smaller or more concentrated fecal deposits.

      (Koyama et al., 2021)

      Expression of capaRdsRNA.Scer\UAS under the control of Scer\GAL4c42 results in significantly decreased malpighian tubule fluid transport rates upon stimulation with the capa1 peptide.

      Flies expressing capaRdsRNA.Scer\UAS under the control of Scer\GAL4Uro.PT exhibit extended survival compared to controls in response to starvation/dessication stress.

      (Terhzaz et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      CapaRRNAi.UAS
      CapaRRNAi
      (Koyama et al., 2021)
      CapaRdsRNA.Scer\UAS
      CapaRdsRNA.UAS
      capaRdsRNA.Scer\UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (4)