FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\garzUAS.B
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General Information
Symbol
Dmel\garzUAS.B
Species
D. melanogaster
Name
FlyBase ID
FBal0268294
Feature type
allele
Associated gene
Dmel\garz
Associated Insertion(s)
Carried in Construct
P{UAS-garz.PB}
Key Links
Transgenic product class
wild_type
(Armbruster and Luschnig, 2012)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Armbruster and Luschnig, 2012)
Mutagen
in vitro construct
(Armbruster and Luschnig, 2012)
Progenitor genotype
Carried in construct
P{UAS-garz.PB}
Cytology
Description

UASt regulatory sequences drive expression of the garz-PB isoform

(Armbruster and Luschnig, 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
garz
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of garzScer\UAS.B under the control of Scer\GAL4GMR.PF results in a rough eye phenotype.

      Expression of garzScer\UAS.B under the control of one copy of Scer\GAL4btl.PS does not interfere with tracheal lumen dilation in embryos. Expression of garzScer\UAS.B under the control of two copies of Scer\GAL4btl.PS results in embryos with a significant reduction in the diameter of the tracheal dorsal trunk lumen compared to wild type.

      (Armbruster and Luschnig, 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      Scer\GAL4GMR.PF, garzUAS.B has eye phenotype, enhanceable by Arf1UASp.EGFP, Scer\GAL4GMR.PF

      (Armbruster and Luschnig, 2012)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of Arf79FScer\UAS.P\T.T:Avic\GFP-EGFP enhances the rough eye phenotype caused by expression of garzScer\UAS.B under the control of Scer\GAL4GMR.PF results in a rough eye phenotype.

      (Armbruster and Luschnig, 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4btl.PS/garzUAS.B rescues Df(2R)Exel6061/garzR1044

      (Armbruster and Luschnig, 2012)
      Comments

      Expression of garzScer\UAS.B under the control of Scer\GAL4btl.PS rescues the narrow diameter of the tracheal dorsal trunk lumen which is seen in garzR1044/Df(2R)Exel6061 embryos.

      (Armbruster and Luschnig, 2012)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      garzScer\UAS.B
      garzUAS.B
      Name Synonyms
      Secondary FlyBase IDs
        References (1)