FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\PolE1Ct.UAS.Tag:HA
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General Information
Symbol
Dmel\PolE1Ct.UAS.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0268528
Feature type
allele
Associated gene
Dmel\PolE1
Associated Insertion(s)
Carried in Construct
P{UAS-PolE1.Ct}
Key Links
Transgenic product class
inframe_deletion
(Suyari et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Suyari et al., 2012)
Mutagen
in vitro construct
(Suyari et al., 2012)
Progenitor genotype
Carried in construct
P{UAS-PolE1.Ct}
Cytology
Description

UAS regulatory sequences drive expression of the C-terminal region of DNApol-ε255 (amino acid residues 1001-2236) which is tagged with a Tag:HA epitope.

(Suyari et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
PolE1
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of DNApol-εCt.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4ey.PU has no discernible effect on the adult eye.

      (Suyari et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      PolE1Ct.UAS.Tag:HA/Scer\GAL4ey.PU rescues PolE1NIG.6768R

      (Suyari et al., 2012)
      Comments

      Co-expression of DNApol-εCt.Scer\UAS.T:Ivir\HA1 rescues the small eye phenotype and mitotic cycle defects seen in the eye imaginal disc which are caused by expression of DNApol-εNIG.6768R under the control of Scer\GAL4ey.PU.

      Co-expression of DNApol-εCt.Scer\UAS.T:Ivir\HA1 does not rescue the endocycle defects seen in the salivary glands of animals expressing DNApol-εNIG.6768R under the control of Scer\GAL4l(1)BP-1.

      (Suyari et al., 2012)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      DNApol-ε255Ct.Scer\UAS.T:Ivir\HA1
      DNApol-ε255Ct.UAS.Tag:HA
      DNApol-εCt.Scer\UAS.T:Ivir\HA1
      PolE1Ct.UAS.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (1)