FlyBase Allele Report: Dmel\mir-ban[GS]

General Information

Symbol

Dmel\mir-ban^GS

Species

D. melanogaster

Name

FlyBase ID

FBal0268610

Feature type

allele

Associated gene

Dmel\mir-ban

Associated Insertion(s)

P{GSV1}mir-ban^GS

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Cho et al., 2006)

Progenitor genotype

Associated Insertion(s)

P{GSV1}mir-ban^GS

Cytology

Description

The P{GSV1} element has been inserted 14kb upstream of the ban stem loop.

(Oh and Irvine, 2011)

The P{GSV1} element is inserted near ban.

(Cho et al., 2006)

Allele components

Component

Use(s)

Inserted element

P{GSV1}

misexpression element

Regulatory region(s)

UASt

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

increased cell number | somatic clone, with Scer\GAL4^FRT.Act5C

(Oh and Irvine, 2011)

increased cell number | third instar larval stage, with Scer\GAL4^repo.PU

(Reddy and Irvine, 2011)

Phenotype Manifest In

eye disc | third instar larval stage, with Scer\GAL4^repo.PU

(Reddy and Irvine, 2011)

larval brain | third instar larval stage, with Scer\GAL4^repo.PU

(Reddy and Irvine, 2011)

larval glial cell | third instar larval stage, with Scer\GAL4^repo.PU

(Reddy and Irvine, 2011)

wing disc | somatic clone, with Scer\GAL4^FRT.Act5C

(Oh and Irvine, 2011)

Detailed Description

Statement

Reference

Growth enhancement is seen in wing disc clones expressing ban^GS under the control of Scer\GAL4^{Scer\FRT.Act5C}.

(Oh and Irvine, 2011)

Expression of ban^GS under the control of Scer\GAL4^repo.PU substantially increases glial cell numbers in the third instar larval eye disc and brain.

(Reddy and Irvine, 2011)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^repo.PU, mir-ban^GS has increased cell number | third instar larval stage phenotype, suppressible by Myc^KK103869, Scer\GAL4^repo.PU

(Reddy and Irvine, 2011)

NOT suppressed by

Statement

Reference

Scer\GAL4^repo.PU, mir-ban^GS has increased cell number | third instar larval stage phenotype, non-suppressible by yki^KK109756/Scer\GAL4^repo.PU

(Reddy and Irvine, 2011)

Suppressor of

Statement

Reference

mir-ban^GS/Scer\GAL4^FRT.Act5C is a suppressor of visible | adult stage phenotype of Scer\GAL4^GMR.PF, brk^UAS.cJa

(Oh and Irvine, 2011)

mir-ban^GS/Scer\GAL4^FRT.Act5C is a suppressor of decreased cell number | somatic clone phenotype of Scer\GAL4^FRT.Act5C, brk^UAS.cJa

(Oh and Irvine, 2011)

mir-ban^GS/Scer\GAL4^FRT.Act5C is a suppressor of abnormal size | adult stage phenotype of Scer\GAL4^GMR.PF, brk^UAS.cJa

(Oh and Irvine, 2011)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^repo.PU, mir-ban^GS has eye disc | third instar larval stage phenotype, suppressible by Myc^KK103869, Scer\GAL4^repo.PU

(Reddy and Irvine, 2011)

Scer\GAL4^repo.PU, mir-ban^GS has larval glial cell | third instar larval stage phenotype, suppressible by Myc^KK103869, Scer\GAL4^repo.PU

(Reddy and Irvine, 2011)

NOT suppressed by

Statement

Reference

Scer\GAL4^repo.PU, mir-ban^GS has eye disc | third instar larval stage phenotype, non-suppressible by yki^KK109756/Scer\GAL4^repo.PU

(Reddy and Irvine, 2011)

Scer\GAL4^repo.PU, mir-ban^GS has larval glial cell | third instar larval stage phenotype, non-suppressible by yki^KK109756/Scer\GAL4^repo.PU

(Reddy and Irvine, 2011)

Suppressor of

Statement

Reference

mir-ban^GS/Scer\GAL4^FRT.Act5C is a suppressor of wing disc | somatic clone phenotype of Scer\GAL4^FRT.Act5C, brk^UAS.cJa

(Oh and Irvine, 2011)

mir-ban^GS/Scer\GAL4^FRT.Act5C is a suppressor of eye phenotype of Scer\GAL4^GMR.PF, brk^UAS.cJa

(Oh and Irvine, 2011)

Additional Comments

Genetic Interactions

Statement

Reference

Expression of ban^GS suppresses the underproliferation seen when brk^Scer\UAS.cJa is expressed in wing disc clones under the control of Scer\GAL4^{Scer\FRT.Act5C}. The eye growth defects seen when brk^Scer\UAS.cJa is expressed under the control of Scer\GAL4^GMR.PF are also rescued.

(Oh and Irvine, 2011)

Expression of yki^KK109756 does not suppress the increase in glial cell number seen in the larval eye disc when ban^GS is expressed under the control of Scer\GAL4^repo.PU.

Expression of dm^KK103869 (co-expressed with Dcr-2^Scer\UAS.cDa) suppresses the increase in glial cell number seen in larval eye discs expressing ban^GS under the control of Scer\GAL4^repo.PU.

(Reddy and Irvine, 2011)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

ban^GS

mir-ban^GS

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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