FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Hnf4sfGFP,Tag:FLAG
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General Information
Symbol
Dmel\Hnf4sfGFP,Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0268878
Feature type
allele
Associated gene
Dmel\Hnf4
Associated Insertion(s)
Carried in Construct
PBac{Hnf4-GFP.FLAG}
Key Links
Transgenic product class
genomic_DNA
(Spokony and White, 2012.5.22)
wild_type
(Spokony and White, 2012.5.22)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Spokony and White, 2012.5.22)
wild_type
(Spokony and White, 2012.5.22)
Mutagen
in vitro construct
(Spokony and White, 2012.5.22)
Progenitor genotype
Carried in construct
PBac{Hnf4-GFP.FLAG}
Cytology
Description

Genomic fragment including the Hnf4 gene, from BAC clone CH321-61C16. A sfGFP-Tag:FLAG tag cassette has been introduced at the C-terminal end of the Hnf4 gene, such that protein isoforms A, B, C and D are tagged.

(Spokony and White, 2012.5.22)
Allele components
Component
Use(s)
Regulatory region(s)
Hnf4
Encoded product / tool
Hnf4
Tagged with
sfGFP
Tag:FLAG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Two copies of Hnf4T:Avic\GFP-SF,T:Zzzz\FLAG restores normal insulin signaling responses but does not rescue hyperglycemia and elevated glycogen levels in Sirt14.5/Sirt12A-7-11 flies.

      (Palu and Thummel, 2016)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Hnf4T:Avic\GFP-SF,T:Zzzz\FLAG
      Hnf4sfGFP,Tag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (4)