FlyBase Allele Report: Dmel\Ack-like[NIG.3969R]

General Information

Symbol

Dmel\Ack-like^NIG.3969R

Species

D. melanogaster

Name

FlyBase ID

FBal0269975

Feature type

allele

Associated gene

Dmel\Ack-like

Associated Insertion(s)

Carried in Construct

P{NIG.3969R}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Zahedi et al., 2008)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Zahedi et al., 2008)

Mutagen

in vitro construct

(Zahedi et al., 2008)

Progenitor genotype

Carried in construct

P{NIG.3969R}

Cytology

Description

UASt regulatory sequences drive expression of an Ack-like RNAi construct.

(Zahedi et al., 2008)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-3969R

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Other

Statement

Reference

Ack-like^NIG.3969R, Ack^10b, Scer\GAL4^c381 has embryo | dorsal closure stage phenotype

(Zahedi et al., 2008)

Ack-like^NIG.3969R, Ack^NIG.14992R, Scer\GAL4^c381 has embryonic/first instar larval cuticle phenotype

(Zahedi et al., 2008)

Ack-like^NIG.3969R, Ack^NIG.14992R, Scer\GAL4^hs.PU has embryo | dorsal closure stage phenotype

(Zahedi et al., 2008)

Additional Comments

Genetic Interactions

Statement

Reference

Embryos co-expressing Ack^NIG.14992R and Ack-like^NIG.3969R under the control of either Scer\GAL4^hs.PB or Scer\GAL4^c381 often fail to secrete cuticle. Those that do sometimes have dorsal defects in the cuticle.

Embryos expressing Ack-like^NIG.3969R under the control of Scer\GAL4^c381 in an Ack^10b background often fail to secrete cuticle. Those that do sometimes have dorsal defects in the cuticle.

(Zahedi et al., 2008)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

NIG-Fly

3969R-1

P{NIG.3969R}1

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Ack-like^NIG.3969R

PR2^NIG.3969R

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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