FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Hsap\LLGL1UAS.cGa
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General Information
Symbol
Hsap\LLGL1UAS.cGa
Species
H. sapiens
Name
Saccharomyces cerevisiae UAS construct a of Grifoni
FlyBase ID
FBal0269987
Feature type
allele
Associated gene
Hsap\LLGL1
Associated Insertion(s)
Carried in Construct
P{UAS-Hugl1.G}
Key Links
Transgenic product class
cDNA
(Grifoni et al., 2004)
wild_type
(Grifoni et al., 2004)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Grifoni et al., 2004)
wild_type
(Grifoni et al., 2004)
Mutagen
in vitro construct
(Grifoni et al., 2004)
Progenitor genotype
Carried in construct
P{UAS-Hugl1.G}
Cytology
Description

UAS regulatory sequences drive expression of a Hsap\LLGL1 cDNA.

(Grifoni et al., 2004)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Hsap\LLGL1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Scer\GAL4Act5C.PU/Hsap\LLGL1UAS.cGa is a suppressor of lethal phenotype of l(2)gl4

      (Grifoni et al., 2004)
      NOT Suppressor of
      Statement
      Reference

      Hsap\LLGL1UAS.cGa/Scer\GAL4ey.PH is a non-suppressor of lethal | somatic clone | pharate adult stage phenotype of l(2)gl4

      (Grifoni et al., 2004)
      Phenotype Manifest In
      Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Flies containing homozygous l(2)gl4 clones generated using the EGUF system (this generates eye discs composed exclusively of homozygous tissue) which are also expressing Hsap\LLGL1Scer\UAS.cGa under the control of Scer\GAL4ey.PH are recovered as pharate adults but they show a partial eversion of the head with the development of rudimentary eyes.

      l(2)gl4 homozygotes that are expressing Hsap\LLGL1Scer\UAS.cGa under the control of Scer\GAL4Act5C.PU either eclose into viable adults (46%) or are recovered as completely developed pharate adults.

      (Grifoni et al., 2004)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Hsap\LLGL1Scer\UAS.cGa
      Hsap\LLGL1UAS.cGa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Grifoni
      Secondary FlyBase IDs
        References (1)