FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\tkvUbi-p63E.Tag:HA
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General Information
Symbol
Dmel\tkvUbi-p63E.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0270122
Feature type
allele
Associated gene
Dmel\tkv
Associated Insertion(s)
Carried in Construct
P{Ubi-tkv.HA}
Key Links
Transgenic product class
wild_type
(Ogiso et al., 2011)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Ogiso et al., 2011)
Mutagen
in vitro construct
(Ogiso et al., 2011)
Progenitor genotype
Carried in construct
P{Ubi-tkv.HA}
Cytology
Description

A 2.0kb Ubi-p63E promoter fragment drives expression of a full-length tkv coding region tagged at the C-terminal end with Tag:HA. The Ubi-p63E promoter contains 660bp upstream of Ubi-p63E and the 5' portion of Ubi-p63E.

(Ogiso et al., 2011)
Allele components
Component
Use(s)
Regulatory region(s)
Ubi-p63E
Encoded product / tool
tkv
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The presence of tkvUbi-p63E.T:Ivir\HA1 in a wild-type background results in the L2 wing vein appearing slightly closer to the anterior-posterior boundary compared to controls.

      Adult wings from flies carrying tkvUbi-p63E.T:Ivir\HA1 appear relatively normal with respect to wing pattern and size, with the exception that the distal region is more pointed than in wild-type and a portion of a vein is missing. The position of the L2 wing vein is significantly closer to the anterior-posterior boundary in tkvUbi-p63E.T:Ivir\HA1 flies compared to wild-type imaginal discs. Increasing the tkvUbi-p63E.T:Ivir\HA1 copy number does not alter the position of the L2 wing vein.

      (Ogiso et al., 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      tkvUbi-p63E.Tag:HA is a suppressor of wing vein L2 phenotype of Dad212

      (Ogiso et al., 2011)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The position of the L2 wing vein in Dad212 moves towards the anterior-posterior boundary as the copy number of tkvUbi-p63E.T:Ivir\HA1 increases.

      (Ogiso et al., 2011)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      tkvUbi-p63E.Tag:HA rescues tkv4

      (Ogiso et al., 2011)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      tkvUbi-p63E.T:Ivir\HA1
      tkvUbi-p63E.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (1)