FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\orb2+t18.7
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General Information
Symbol
Dmel\orb2+t18.7
Species
D. melanogaster
Name
FlyBase ID
FBal0276756
Feature type
allele
Associated gene
Dmel\orb2
Associated Insertion(s)
Carried in Construct
P{orb2+t18.7}
Also Known As
pattB-Orb2
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Majumdar et al., 2012)
Progenitor genotype
Carried in construct
P{orb2+t18.7}
Cytology
Description

An 18.7kb wild-type genomic transgene that contains 560bp of the exons specific to the orb2 E-H isoforms and none of the I isoform.

(Majumdar et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
orb2
Encoded product / tool
orb2
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      orb2Δ homozygotes that express orb2+t18.7 do not exhibit a significant decrease in long-term memory in male courtship suppression assays, as compared to controls.

      (Gill et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      orb2+t18.7 rescues orb2Δ

      (Majumdar et al., 2012)
      Comments

      Expression of orb2+t18.7 rescues the courtship behavior defects seen in orb2Δ mutant males.

      Expression of orb2+t18.7 completely rescues the defects in olfactory memory seen in orb2Δ mutant flies.

      (Majumdar et al., 2012)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      orb2+t18.7
      Name Synonyms
      Secondary FlyBase IDs
        References (2)