FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Vha100-1N509Q.UAS
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General Information
Symbol
Dmel\Vha100-1N509Q.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0277043
Feature type
allele
Associated gene
Dmel\Vha100-1
Associated Insertion(s)
Carried in Construct
P{UAS-Vha100-1.N509Q}
Key Links
Transgenic product class
missense_variant
(Coen et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Coen et al., 2012)
Mutagen
in vitro construct
(Coen et al., 2012)
Progenitor genotype
Carried in construct
P{UAS-Vha100-1.N509Q}
Cytology
Description

UASt regulatory sequences drive expression of a mutant for of Vha100-1 in which the asparagine at amino acid 509 has been replaced by glutamine.

(Coen et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Vha100-1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Vha100-1N509Q.UAS/Scer\GAL4GMR.PF rescues Vha100-14

      (Coen et al., 2012)

      Scer\GAL4elav-C155/Vha100-1N509Q.UAS rescues Df(3R)3450/Vha100-14

      (Coen et al., 2012)
      Comments

      Expression of Vha100-1N509Q.Scer\UAS under the control of Scer\GAL4GMR.PF fully rescues the neurotransmission defects seen when photoreceptors are mutant for Vha100-14.

      Expression of Vha100-1N509Q.Scer\UAS under the control of Scer\GAL4elav-C155 fully rescues the lethality seen in Vha100-14/Df(3R)3450 mutants.

      (Coen et al., 2012)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Vha100-1N509Q.Scer\UAS
      Vha100-1N509Q.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)