FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\lin-52GFP
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General Information
Symbol
Dmel\lin-52GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0277118
Feature type
allele
Associated gene
Dmel\lin-52
Associated Insertion(s)
Carried in Construct
P{lin-52-GFP}
Key Links
Transgenic product class
genomic_DNA
(Lewis et al., 2012)
wild_type
(Lewis et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Lewis et al., 2012)
wild_type
(Lewis et al., 2012)
Mutagen
in vitro construct
(Lewis et al., 2012)
Progenitor genotype
Carried in construct
P{lin-52-GFP}
Cytology
Description

A 1.6 genomic fragment containing the lin-52 promoter and coding region is tagged at its C-terminal end with GFP.

(Lewis et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
lin-52
Encoded product / tool
lin-52
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      epitope tag
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      third instar larval stage
      eye disc
      (Lewis et al., 2012)
      imaginal disc
      (Lewis et al., 2012)
      larval brain
      (Lewis et al., 2012)
      embryonic/larval salivary gland
      (Lewis et al., 2012)
      adult stage | female
      egg chamber
      (Lewis et al., 2012)
      Additional Information
      Statement
      Reference

      lin-52 is present in the nuclei of ovarian germ line and somatic cells. It is also observed in dipoid tissues such as third instar larval imaginal discs and brain and in polytene tissues, including the salivary glands.

      (Lewis et al., 2012)
       
      Marker for
      Reflects expression of
      lin-52
      (Lewis et al., 2012)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      lin-52GFP rescues lin-5293

      (Lewis et al., 2012)
      Comments

      Expression of lin-52T:Avic\GFP rescues the lethality seen in lin-5293 mutant larvae.

      (Lewis et al., 2012)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      lin-52GFP
      lin-52T:Avic\GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)