FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mir-14UAS.pLUC
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General Information
Symbol
Dmel\mir-14UAS.pLUC
Species
D. melanogaster
Name
FlyBase ID
FBal0277405
Feature type
allele
Associated gene
Dmel\mir-14
Associated Insertion(s)
Carried in Construct
P{UAS-LUC-mir-14.T}
Key Links
Transgenic product class
wild_type
(Bejarano et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Bejarano et al., 2012)
Mutagen
in vitro construct
(Bejarano et al., 2012)
Progenitor genotype
Carried in construct
P{UAS-LUC-mir-14.T}
Cytology
Description

UAS regulatory sequences drive expression of Ppyr\LUC followed by a genomic fragment containing the mir-14 pre-miRNA hairpin.

(Bejarano et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
mir-14
Tagged with
pLUC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of mir-14Scer\UAS.T:Ppyr\LUC under the control of Scer\GAL4Bx-MS1096 results in slightly curved wings.

      Expression of mir-14Scer\UAS.T:Ppyr\LUC under the control of Scer\GAL4sd-SG29.1 results in curved, spoon-shaped wings. The margin appears slightly irregular.

      Expression of mir-14Scer\UAS.T:Ppyr\LUC under the control of Scer\GAL4ptc-559.1 does not result in a mutant phenotype.

      (Bejarano et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Scer\GAL4L4/mir-14UAS.pLUC is a suppressor of chemical sensitive | dominant phenotype of esgL4

      (Sanchez-Díaz et al., 2015)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Scer\GAL4L4/mir-14UAS.pLUC is a suppressor of abdomen phenotype of esgL4

      (Sanchez-Díaz et al., 2015)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of mir-14Scer\UAS.T:Ppyr\LUC under the control of Scer\GAL4L4 suppresses the cuticle phenotype and nicotine sensitivity seen in esgL4 mutant flies. Viability is unaffected.

      (Sanchez-Díaz et al., 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4fkh.PU/mir-14UAS.pLUC rescues mir-14Δ1

      (Nelson et al., 2014)
      Comments

      Expression of mir-14Scer\UAS.T:Ppyr\LUC under the control of Scer\GAL4fkh.PU rescues the persistent salivary gland phenotype seen in mir-14Δ1 homozygotes 24 hours after pupariation.

      (Nelson et al., 2014)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      mir-14Scer\UAS.T:Ppyr\LUC
      mir-14UAS.pLUC
      Name Synonyms
      Secondary FlyBase IDs
        References (5)