FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mir-312UAS.cluster.DsRed(Unk)
Open Close
General Information
Symbol
Dmel\mir-312UAS.cluster.DsRed(Unk)
Species
D. melanogaster
Name
FlyBase ID
FBal0278048
Feature type
allele
Associated gene
Dmel\mir-312
Associated Insertion(s)
Carried in Construct
P{UAS-DsRed-mir-310+mir-311+mir-312+mir-313.L}
Key Links
Transgenic product class
wild_type
(Bejarano et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Bejarano et al., 2012)
Mutagen
in vitro construct
(Bejarano et al., 2012)
Progenitor genotype
Carried in construct
P{UAS-DsRed-mir-310+mir-311+mir-312+mir-313.L}
Cytology
Description

UAS regulatory sequences drive expression of a DsRed(Unk) fluorescent protein. A genomic fragment containing an miRNA cluster (includes the mir-310, mir-311, mir-312 and mir-313 pre-miRNA hairpins) has been inserted into the DsRed(Unk) 3'UTR.

(Bejarano et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
mir-312
Tagged with
DsRed(Unk)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Suppressor of
      Other
      Phenotype Manifest In
      Suppressed by
      Suppressor of
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Clones expressing P{UAS-DsRed-mir-310+mir-311+mir-312+mir-313.L} (carries mir-310Scer\UAS.cluster.T:Disc\RFP, mir-311Scer\UAS.cluster.T:Disc\RFP, mir-312Scer\UAS.cluster.T:Disc\RFP and mir-313Scer\UAS.cluster.T:Disc\RFP) under the control of Scer\GAL4unspecified are difficult to recover in the wing imaginal disc. Co-expression of armS10.Scer\UAS.T:Hsap\MYC significantly rescues the viability of these clones.

      Expression of P{UAS-DsRed-mir-310+mir-311+mir-312+mir-313.L} (carries mir-310Scer\UAS.cluster.T:Disc\RFP, mir-311Scer\UAS.cluster.T:Disc\RFP, mir-312Scer\UAS.cluster.T:Disc\RFP and mir-313Scer\UAS.cluster.T:Disc\RFP) under the control of Scer\GAL4bbg-C96 results in wing notching.

      Co-expression of armS10.Scer\UAS.T:Hsap\MYC rescues the wing notching seen in flies expressing P{UAS-DsRed-mir-310+mir-311+mir-312+mir-313.L} (carries mir-310Scer\UAS.cluster.T:Disc\RFP, mir-311Scer\UAS.cluster.T:Disc\RFP, mir-312Scer\UAS.cluster.T:Disc\RFP and mir-313Scer\UAS.cluster.T:Disc\RFP) under the control of Scer\GAL4bbg-C96.

      Co-expression of P{UAS-DsRed-mir-310+mir-311+mir-312+mir-313.L} (carries mir-310Scer\UAS.cluster.T:Disc\RFP, mir-311Scer\UAS.cluster.T:Disc\RFP, mir-312Scer\UAS.cluster.T:Disc\RFP and mir-313Scer\UAS.cluster.T:Disc\RFP) suppresses the specification of extra wing margin bristles caused by expression of armS10.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4bbg-C96.

      (Pancratov et al., 2013)

      Expression of P{UAS-DsRed-mir-310+mir-311+mir-312+mir-313.L} under the control of Scer\GAL4Bx-MS1096 results in wings which are curved, small and folded.

      (Bejarano et al., 2012)
      Xenogenetic Interactions
      Statement
      Reference

      Co-expression of BacA\p35Scer\UAS.cHa rescues the viability of clones in the wing disc expressing P{UAS-DsRed-mir-310+mir-311+mir-312+mir-313.L} (carries mir-310Scer\UAS.cluster.T:Disc\RFP, mir-311Scer\UAS.cluster.T:Disc\RFP, mir-312Scer\UAS.cluster.T:Disc\RFP and mir-313Scer\UAS.cluster.T:Disc\RFP) under the control of Scer\GAL4unspecified. The recovered clones are small, consisting of just one to three cells and appear to be delaminating from the epithelial plane.

      (Pancratov et al., 2013)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      mir-312Scer\UAS.cluster.T:Disc\RFP
      mir-312UAS.cluster.DsRed(Unk)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)