FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\tsuΔ3-5
Open Close
General Information
Symbol
Dmel\tsuΔ3-5
Species
D. melanogaster
Name
FlyBase ID
FBal0278194
Feature type
allele
Associated gene
Dmel\tsu
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Parma et al., 2007)
Mutagen
P-element activity
(Parma et al., 2007)
Progenitor genotype
P{EP}tsuEP567
(Parma et al., 2007)
Cytology
Description

Imprecise excision of the progenitor insertion, resulting in a 880bp deletion that extends upstream from the original insertion site, eliminating the transcriptional promoter and all the the 3' most 72bp of the tsu 5'UTR.

(Parma et al., 2007)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous female germline clones develop to stage 3-4 of oogenesis, and fusome development appears normal. Entry into meiosis is normal in the mutant cysts, but 84% of the clones retain synaptonemal complexes in four adjacent cells in regions 2b and 3 of the germarium. In contrast to wild type, centrosomes are not concentrated within single cells in regions 2b and 3 of the germarium, but are evenly distributed.

      (Parma et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Female germline clones that are doubly mutant for tsuΔ3-5 and magoSHL1 have a phenotype indistinguishable from that of magoSHL1 single mutant clones.

      (Parma et al., 2007)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      tsuΔ3-5
      (Parma et al., 2007)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)