FlyBase Allele Report: Dmel\Fmr1[+tLa]

General Information

Symbol

Dmel\Fmr1^+tLa

Species

D. melanogaster

Name

FlyBase ID

FBal0278295

Feature type

allele

Associated gene

Dmel\Fmr1

Associated Insertion(s)

Carried in Construct

P{mir-277-Fmr1^+tLa}

Key Links

Transgenic product class

genomic_DNA

(Liu et al., 2012)

wild_type

(Liu et al., 2012)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

genomic_DNA

(Liu et al., 2012)

wild_type

(Liu et al., 2012)

Mutagen

in vitro construct

(Liu et al., 2012)

Progenitor genotype

Carried in construct

P{mir-277-Fmr1^+tLa}

Cytology

Description

A genomic fragment containing Fmr1.

(Liu et al., 2012)

Allele components

Component

Use(s)

Regulatory region(s)

Fmr1

Encoded product / tool

Fmr1

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal heat stress response | conditional, with mir-277^+tLa, mir-34^null

(Liu et al., 2012)

abnormal locomotor behavior | adult stage | conditional, with mir-277^+tLa, mir-34^null

(Liu et al., 2012)

abnormal neuroanatomy | conditional, with mir-277^+tLa, mir-34^null

(Liu et al., 2012)

short lived, with mir-277^+tLa, mir-34^null

(Liu et al., 2012)

viable, with mir-277^+tLa, mir-34^null

(Liu et al., 2012)

Phenotype Manifest In

adult brain | conditional, with mir-277^+tLa, mir-34^null

(Liu et al., 2012)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Fmr1^+tLa, mir-277^+tLa, mir-34^null has short lived phenotype, suppressible | partially by Eip74EF^BG01805

(Liu et al., 2012)

Fmr1^+tLa, mir-277^+tLa, mir-34^null has abnormal neuroanatomy | conditional phenotype, suppressible | partially by Eip74EF^BG01805

(Liu et al., 2012)

NOT suppressed by

Statement

Reference

Fmr1^+tLa, mir-277^+tLa, mir-34^null has short lived phenotype, non-suppressible by Eip74EF[+]/Eip74EF^BG01805

(Liu et al., 2012)

Fmr1^+tLa, mir-277^+tLa, mir-34^null has abnormal neuroanatomy | conditional phenotype, non-suppressible by Eip74EF[+]/Eip74EF^BG01805

(Liu et al., 2012)

Phenotype Manifest In

Suppressed by

Statement

Reference

Fmr1^+tLa, mir-277^+tLa, mir-34^null has adult brain | conditional phenotype, suppressible | partially by Eip74EF^BG01805

(Liu et al., 2012)

NOT suppressed by

Statement

Reference

Fmr1^+tLa, mir-277^+tLa, mir-34^null has adult brain | conditional phenotype, non-suppressible by Eip74EF[+]/Eip74EF^BG01805

(Liu et al., 2012)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Fmr1^+tLa

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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