FB2026_02 , released June 18, 2026
Allele: Dmel\Abca3HMS01796
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General Information
Symbol
Dmel\Abca3HMS01796
Species
D. melanogaster
Name
FlyBase ID
FBal0278914
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-dABCA-IR666-672
Key Links
Genomic Maps

Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

UAS regulatory sequences drive expression of a short inverted repeat.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 1 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of Abca3HMS01796 under the control of Scer\GAL4elav.PLu leads to an increase in the active zone density at neuromuscular junctions (of muscle 4 of the A3 and A4 segment) in third instar larvae when compared to controls.

Expression of ABCAHMS01796 under the control of either Scer\GAL4GR1 or Scer\GAL4nos.UTR.T:Hsim\VP16 does not induce any nurse cell clearance defect in mutant stage 14 egg chambers and like in wild-type all the germ-line derived nurse cells have undergone programmed cell death and been cleared by this stage.

Expression from one copy of ABCAHMS01796 under the control of Scer\GAL4elav.PLu leads to a significant increase in average distance between male adults (not between female adults), despite no significant changes in locomotor ability, as compared to controls. Reared under 12h:12h light:dark cycles, these adults present mild increases in evening peak activity (including an early onset of activity), and in midday siesta activity, but not in morning activity peak, and a mild decrease in night time sleep, as compared to controls.

The neuromuscular junctions of third instar larvae expressing from one copy of ABCAHMS01796 under the control of Scer\GAL4elav.PLu exhibit a small but significant increase in the number of satellite boutons, but exhibit no obvious changes in the number of mature boutons, or in either the number or length of branches, as compared to controls.

External Data
Interactions
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Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
ABCAHMS01796
Abca3HMS01796
CG1718HMS01796
Name Synonyms
Secondary FlyBase IDs
    References (6)