FlyBase Allele Report: Dmel\jub[HMS02335]

General Information

Symbol

Dmel\jub^HMS02335

Species

D. melanogaster

Name

FlyBase ID

FBal0279334

Feature type

allele

Associated gene

Dmel\jub

Associated Insertion(s)

Carried in Construct

P{TRiP.HMS02335}

Also Known As

HMS02335

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMS02335}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMS02335

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

exacerbates cancer

modeled by Rbf^HMS03004

(Parkhitko et al., 2021)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell shape | larval stage, with Scer\GAL4^hh.PU

(Rauskolb et al., 2022)

increased cell death | third instar larval stage, with Scer\GAL4^en-e16E

(Sun et al., 2020)

visible | adult stage, with Scer\GAL4^nub.PU

(Rauskolb et al., 2022)

Phenotype Manifest In

epithelial cell of wing disc | larval stage, with Scer\GAL4^hh.PU

(Rauskolb et al., 2022)

wing, with Scer\GAL4^nub.PU

(Rauskolb et al., 2022)

wing disc | larval stage, with Scer\GAL4^hh.PU

(Rauskolb et al., 2022)

wing disc | third instar larval stage, with Scer\GAL4^en-e16E

(Sun et al., 2020)

Detailed Description

Statement

Reference

Expression of jub^HMS02335 under the control of Scer\GAL4^en-e16E leads to increased cell death in third instar larval wing discs.

(Sun et al., 2020)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

jub^HMS02335 is rescued by Scer\GAL4^nub.PU/jub^{UASp.FL.msVenus}

(Rauskolb et al., 2022)

jub^HMS02335 is rescued by Scer\GAL4^hh.PU/jub^{UASp.FL.msVenus}

(Rauskolb et al., 2022)

jub^HMS02335 is rescued by Scer\GAL4^nub.PU/jub^{preLIM+12.UASp.msVenus}

(Rauskolb et al., 2022)

jub^HMS02335 is rescued by jub^{preLIM+23.UASp.msVenus}/Scer\GAL4^hh.PU

(Rauskolb et al., 2022)

Partially rescued by

jub^HMS02335 is partially rescued by Scer\GAL4^hh.PU/jub^{preLIM+12.UASp.msVenus}

(Rauskolb et al., 2022)

jub^HMS02335 is partially rescued by jub^{preLIM+23.UASp.msVenus}/Scer\GAL4^nub.PU

(Rauskolb et al., 2022)

Not rescued by

jub^HMS02335 is not rescued by Scer\GAL4^nub.PU/jub^{preLIM+1.UASp.msVenus}

(Rauskolb et al., 2022)

jub^HMS02335 is not rescued by Scer\GAL4^nub.PU/jub^{preLIM+13.UASp.msVenus}

(Rauskolb et al., 2022)

jub^HMS02335 is not rescued by Scer\GAL4^hh.PU/jub^{preLIM+13.UASp.msVenus}

(Rauskolb et al., 2022)

jub^HMS02335 is not rescued by Scer\GAL4^nub.PU/jub^{preLIM+2.UASp.msVenus}

(Rauskolb et al., 2022)

jub^HMS02335 is not rescued by jub^{preLIM+3.UASp.msVenus}/Scer\GAL4^nub.PU

(Rauskolb et al., 2022)

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

41938

y¹ v¹; P{TRiP.HMS02335}attP40

NIG-Fly

HMS02335

y¹ v¹; P{TRiP.HMS02335}attP40/CyO

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

jub^HMS02335

(Forest et al., 2018)

Name Synonyms

Secondary FlyBase IDs

References (9)

Report Sections

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