FB2026_02 , released June 18, 2026
Allele: Dmel\ApoltpRNAi.UAS.I
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General Information
Symbol
Dmel\ApoltpRNAi.UAS.I
Species
D. melanogaster
Name
FlyBase ID
FBal0279534
Feature type
allele
Associated gene
Dmel\Apoltp
Associated Insertion(s)
Carried in Construct
P{UAS(-FRT)Apoltp.RNAi.I}
Also Known As
LTP RNAi
Key Links
Transgenic product class
RNAi_reagent
(Palm et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Palm et al., 2012)
Mutagen
FLPase
(Palm et al., 2012)
Progenitor genotype
ApoltpRNAi.FRT.UAS.I
(Palm et al., 2012)
Carried in construct
P{UAS(-FRT)Apoltp.RNAi.I}
Cytology
Description

The FRT>HcRed1>FRT cassette has been excised, allowing the UASt regulatory sequences to drive expression of an inverted repeat of Apoltp nucleotides 425-944 (this dsRNA targets the ApoLTPI cleavage product of the Apoltp precursor).

(Palm et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Apoltp
Also carries
FRT
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of ApoltpdsRNA.Scer\UAS.I in the fat body under the control of Scer\GAL4Adh.PF (initiated by heat shock during the larval stages) results in dramatic enlargement of the neutral fat droplets in the larval posterior midgut.

      (Palm et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      ApoltpRNAi.UAS.I
      ApoltpdsRNA.Scer\UAS.I
      ApoltpdsRNA.UAS.I
      Name Synonyms
      Secondary FlyBase IDs
        References (3)