FlyBase Allele Report: Scer\GAL4[Adh.PF]

General Information

Symbol

Scer\GAL4^Adh.PF

Species

S. cerevisiae

Name

Alcohol dehydrogenase promoter construct of Fischer

FlyBase ID

FBal0040473

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{GAL4-Adh.Dmul}

Also Known As

Adh-Gal4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Fischer et al., 1988)

Progenitor genotype

Carried in construct

P{GAL4-Adh.Dmul}

Cytology

Description

An Adh promoter controls expression of a GAL4 driver.

(Fischer et al., 1988)

Allele components

Component

Use(s)

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

third instar larval stage

larval digestive system

(Britton et al., 2002)

larval tracheal system

(Britton et al., 2002)

embryonic/larval fat body

(Britton et al., 2002)

adult stage

adult fat body

(Moraru et al., 2017)

Additional Information

Statement

Reference

Drives expression in larval and adult fat bodies.

(FlyBase Curators, 2017)

In third instar larva, expressed predominantly in fat body; expressed also in trachea and in a few cells in the gut.

(Britton et al., 2002)

Marker for

Reflects expression of

Adh

(Britton et al., 2002)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal feeding behavior, with InR^UAS.cHa

(Britton et al., 2002)

abnormal feeding behavior, with Pi3K92E^{UAS.Tag:MYC,Tag:PM(hKRAS)}

(Britton et al., 2002)

abnormal feeding behavior, with Pi3K92E^UAS.Tag:MYC

(Britton et al., 2002)

abnormal starvation stress response, with Lnk^UAS.cSa

(Song et al., 2010)

fertile, with cv-d^GD1820

(Palm et al., 2012)

fertile, with Pi3K92E^UAS.Tag:MYC

(Britton et al., 2002)

lethal, with InR^UAS.cHa

(Britton et al., 2002)

lethal | larval stage, with Dronc^UAS.EGFP

(Liu et al., 2009)

lethal | P-stage, with Dronc^UAS.EGFP

(Liu et al., 2009)

viable, with Pi3K92E^UAS.Tag:MYC

(Britton et al., 2002)

Phenotype Manifest In

embryonic/larval fat body, with apolpp^{RNAi.ApoLII.UAS}

(Panakova et al., 2005)

embryonic/larval fat body | third instar larval stage, with apolpp^{RNAi.ApoLI.UAS}

(Palm et al., 2012)

embryonic/larval fat body | third instar larval stage, with Apoltp^RNAi.UAS.II

(Palm et al., 2012)

embryonic/larval fat body | wandering third instar larval stage, with Dronc^UAS.EGFP

(Liu et al., 2009)

embryonic/larval fat body | wandering third instar larval stage, with Met^UAS.cBa, Met^W3

(Liu et al., 2009)

embryonic/larval hemolymph | third instar larval stage, with FASN1^GD14739

(Palm et al., 2012)

embryonic/larval midgut | third instar larval stage, with apolpp^{RNAi.ApoLI.UAS}

(Palm et al., 2012)

embryonic/larval midgut | third instar larval stage, with apolpp^{RNAi.ApoLII.UAS}

(Palm et al., 2012)

embryonic/larval midgut | third instar larval stage, with Apoltp^RNAi.UAS.I

(Palm et al., 2012)

embryonic/larval midgut | third instar larval stage, with Apoltp^RNAi.UAS.II

(Palm et al., 2012)

fat body, with Lsd2^UAS.cGa

(Gronke et al., 2003)

larval brain | third instar larval stage, with Apoltp^RNAi.UAS.II

(Palm et al., 2012)

lipid droplet, with apolpp^{RNAi.ApoLII.UAS}

(Panakova et al., 2005)

wing disc, with apolpp^{RNAi.ApoLII.UAS}

(Panakova et al., 2005)

wing disc | third instar larval stage, with Apoltp^RNAi.UAS.II

(Palm et al., 2012)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^Adh.PF/Lnk^UAS.cSa rescues Lnk^d07478

(Song et al., 2010)

Partially rescues

THADA^UAS.cMa/Scer\GAL4^Adh.PF partially rescues THADA^KO1

(Moraru et al., 2017)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

81121

P{GAL4-Adh.Dmul}2/CyO; ry⁵⁰⁶

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

GAL4^Adh.PF

Scer\GAL4^Adh.PF

Name Synonyms

Alcohol dehydrogenase promoter construct of Fischer

Secondary FlyBase IDs

References (22)

Report Sections

Open Close