FB2026_02 , released June 18, 2026
Allele: Dmel\THADAUAS.cMa
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General Information
Symbol
Dmel\THADAUAS.cMa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Moraru
FlyBase ID
FBal0326347
Feature type
allele
Associated gene
Dmel\THADA
Associated Insertion(s)
Carried in Construct
P{UAS-THADA.M}
Key Links
Transgenic product class
genomic_DNA
(Moraru et al., 2017)
wild_type
(Moraru et al., 2017)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Moraru et al., 2017)
wild_type
(Moraru et al., 2017)
Mutagen
in vitro construct
(Moraru et al., 2017)
Progenitor genotype
Carried in construct
P{UAS-THADA.M}
Cytology
Description

UASt regulates expression of the genomic sequence of THADA.

(Moraru et al., 2017)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
THADA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      THADAUAS.cMa/Scer\GAL4elav.PU partially rescues THADAKO1

      (Moraru et al., 2017)

      THADAUAS.cMa/Scer\GAL4da.PU partially rescues THADAKO1

      (Moraru et al., 2017)

      THADAUAS.cMa/Scer\GAL4mir-278-Gal4KI partially rescues THADAKO1

      (Moraru et al., 2017)

      THADAUAS.cMa/Scer\GAL4Adh.PF partially rescues THADAKO1

      (Moraru et al., 2017)
      Comments

      The obesity (measured as a fat/protein ratio) as well increased food intake characteristic for THADAKO1 mutant adults are partially rescued by expression of THADAScer\UAS.cMa controlled by either Scer\GAL4elav.PU or Scer\GAL4da.PU. The increased adiposity of THADAKO1 mutants is also improved by Scer\GAL4mir-278-Gal4KI (while the increased food intake is not rescued) or Scer\GAL4Adh.PF-driven expression.

      The poor recovery from cold-induced paralysis displayed by THADAKO1 mutants is rescued by expression of THADAScer\UAS.cMa under the control of Scer\GAL4da.PU in the mutant background.

      (Moraru et al., 2017)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      THADAScer\UAS.cMa
      THADAUAS.cMa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Moraru
      Secondary FlyBase IDs
        References (2)