negative regulation of lipid storage - negative regulation of endoplasmic reticulum calcium ion concentration - adaptive thermogenesis - negative regulation of calcium-transporting ATPase activity - binds the sarco/ER Ca2+ ATPase (SERCA) and acts on it as an uncoupler
Gene model reviewed during 5.39
Multiphase exon postulated: exon reading frame differs in alternative transcripts; overlap >20aa.
Gene model reviewed during 5.53
None of the polypeptides share 100% sequence identity.
Interacts with SERCA.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\THADA using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\THADA in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: THADA CG15618
Named 'THADA' after the human ortholog.