Approximately 95% of larvae expressing Scer\GAL4Adh.PF-driven NcScer\UAS.T:Avic\GFP-EGFP in the fat body die during different larval stages. The remaining animals die at the pupal stage. A significant portion of fat body cells in these mutants display apoptosis at the early wandering third instar larval stage.
NcScer\UAS.T:Avic\GFP-EGFP; Scer\GAL4hs.PB rescues pupariation of most Nc30, Nc11 or Nc51 homozygous larvae. It also rescues cell death in the larval midgut in response to feeding mid-third instar larvae with ecdysone and the normal pattern of cell death of abdominal neuroblasts in the late third instar.