FB2026_03 , released September 17, 2026
Allele: Hsap\PROM1ΔC.UAS.GFP
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General Information
Symbol
Hsap\PROM1ΔC.UAS.GFP
Species
H. sapiens
Name
FlyBase ID
FBal0279599
Feature type
allele
Associated gene
Hsap\PROM1
Associated Insertion(s)
Carried in Construct
P{UAS-hProm1-GFP.ΔC}
Key Links
Transgenic product class
inframe_deletion
(Nie et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Nie et al., 2012)
Mutagen
in vitro construct
(Nie et al., 2012)
Progenitor genotype
Carried in construct
P{UAS-hProm1-GFP.ΔC}
Cytology
Description

UASt regulatory sequences drive expression of Hsap\PROM1 coding sequences where the intracellular C-terminal domain has been deleted and replaced by GFP (the first 9 amino acid residues after the fifth transmembrane domain are retained).

(Nie et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Hsap\PROM1
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Hsap\PROM1ΔC.UAS.GFP/Scer\GAL4GMR.PF is a suppressor of rhabdomere phenotype of prom1

      (Nie et al., 2012)

      Hsap\PROM1ΔC.UAS.GFP/Scer\GAL4GMR.PF is a suppressor of eye phenotype of prom1

      (Nie et al., 2012)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Expression of Hsap\PROM1ΔC.Scer\UAS.T:Avic\GFP in the developing eye under the control of Scer\GAL4GMR.PF suppresses the prom1 mutant eye phenotype.

      (Nie et al., 2012)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Hsap\PROM1ΔC.Scer\UAS.T:Avic\GFP
      Hsap\PROM1ΔC.UAS.GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)