FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\tshΔPLDLS.UAS
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General Information
Symbol
Dmel\tshΔPLDLS.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0279785
Feature type
allele
Associated gene
Dmel\tsh
Associated Insertion(s)
Carried in Construct
PBac{UAS-tsh.ΔPLDLS}
Also Known As
UAS-TshΔPLDLS
Key Links
Transgenic product class
inframe_deletion
(Datta et al., 2011)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Datta et al., 2011)
Mutagen
in vitro construct
(Datta et al., 2011)
Progenitor genotype
Carried in construct
PBac{UAS-tsh.ΔPLDLS}
Cytology
Description

UAS regulatory sequences drive expression of tsh lacking the CtBP binding site. Amino acids 1-187 are fused to amino acids 193-954.

(Datta et al., 2011)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
tsh
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  Alzheimer's disease 1
      modeled by Hsap\APPAβ42.UAS.cUa
      (Moran et al., 2013)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of tshΔPLDLS.Scer\UAS under the control of Scer\GAL4dpp.PS induces ectopic eyes in 11.5% of antennal discs. The ectopic eyes are very small, containing only a handful of ommatidia.

      (Datta et al., 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      tshΔPLDLS.Scer\UAS
      tshΔPLDLS.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (2)