FB2025_02 , released April 17, 2025
Allele: Disc\RFPnerfin-1.13
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General Information
Symbol
Disc\RFPnerfin-1.13
Species
D. sp.
Name
FlyBase ID
FBal0279866
Feature type
allele
Associated gene
Disc\RFP
Associated Insertion(s)
Carried in Construct
P{nerfin-1-RFP.13}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Kuzin et al., 2009)
Progenitor genotype
Carried in construct
P{nerfin-1-RFP.13}
Cytology
Description

The 3'UTR and 3' conserved sequence cluster of nerfin-1 is fused upstream of sequence encoding the DsRed(T4) fluorescent protein tagged with a nuclear localization signal (Tag:NLS(tra)).

(Kuzin et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
nerfin-1_fragment13
Encoded product / tool
DsRed(T4)
Tagged with
Tag:NLS(tra)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage 11
      stage 4 neuroblast | subset
      (Kuzin et al., 2009)
      embryonic ganglion mother cell
      (Kuzin et al., 2009)
      third instar larval stage
      larval neuron | subset of larval brain
      (Kuzin et al., 2009)
      larval neuron | subset of larval optic anlage
      (Kuzin et al., 2009)
      Additional Information
      Statement
      Reference

      DiscRFPnerfin-1.13 is expressed in a subset of neuroblasts and their ganglion mother cells at embryonic stage 11 as well as in a subset of neurons in the larval brain, in particular in the larval optic anlage.

      (Kuzin et al., 2009)
       
      Marker for
      Reflects expression of
      nerfin-1
      (Kuzin et al., 2009)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Disc\RFPnerfin-1.13
      Name Synonyms
      Secondary FlyBase IDs
        References (2)