FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Mmus\Itpr1mut.sponge.UAS.GFP
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General Information
Symbol
Mmus\Itpr1mut.sponge.UAS.GFP
Species
M. musculus
Name
FlyBase ID
FBal0280830
Feature type
allele
Associated gene
Mmus\Itpr1
Associated Insertion(s)
Carried in Construct
P{UAS-GFP-IP3-sponge.mut}
Transgenic product class
inframe_deletion
(Hiramoto and Hiromi, 2006)
missense_variant
(Hiramoto and Hiromi, 2006)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Hiramoto and Hiromi, 2006)
missense_variant
(Hiramoto and Hiromi, 2006)
Mutagen
in vitro construct
(Hiramoto and Hiromi, 2006)
Progenitor genotype
Carried in construct
P{UAS-GFP-IP3-sponge.mut}
Cytology
Description

UAS regulatory sequences drive expression of the IP3-binding domain of Mmus\Itpr1 containing a point mutation in a residue required for binding of inositol 1,4,5 triphosphate (IP3). The protein is tagged with GFP.

(Hiramoto and Hiromi, 2006)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Mmus\Itpr1
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Phenotype Manifest In
      NOT Suppressor of
      Statement
      Reference

      Scer\GAL415J2/Mmus\Itpr1mut.sponge.UAS.GFP is a non-suppressor of dMP2 neuron phenotype of robo11

      (Hiramoto and Hiromi, 2006)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Expression of Mmus\Itpr1mut.sponge.Scer\UAS.T:Avic\GFP under the control of Scer\GAL415J2 does not suppress the dMP2 axon misprojection phenotype seen in homozygous robo1 embryos.

      (Hiramoto and Hiromi, 2006)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Mmus\Itpr1mut.sponge.Scer\UAS.T:Avic\GFP
      Mmus\Itpr1mut.sponge.UAS.GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)