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General Information
Symbol
Dmel\tbrd-11
Species
D. melanogaster
Name
FlyBase ID
FBal0281059
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Insertion into tbrd-1. This results in a premature translation after 281 amino acid residues, with the protein produced consisting of 262 amino acids of tbrd-1 and 19 amino acids encoded by the insertion.

Insertion components
P{EPgy2}tbrd-11
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygous, tbrd-11/Df(3R)ED10893 and tbrd-11/Df(3R)Exel9014 males are completely sterile.

The Nebenkern is larger than the nucleus in early round spermatids in homozygous males. The nuclei of mutant spermatids remain small and round (in contrast to the elongated shape that develops in wild type). In addition, spermatid nuclei are scattered throughout elongated bundles of flagella instead of being clustered at one end as in wild type. Investment cones are formed in homozygous mutants, but individualisation complexes are never seen.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Rescued by
Not rescued by
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (4)