FlyBase Allele Report: Dmel\btl[HMS02656]

General Information

Symbol

Dmel\btl^HMS02656

Species

D. melanogaster

Name

FlyBase ID

FBal0281658

Feature type

allele

Associated gene

Dmel\btl

Associated Insertion(s)

Carried in Construct

P{TRiP.HMS02656}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMS02656}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMS02656

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased cell number | larval stage, with Scer\GAL4^srp.D.cCa

(Tattikota et al., 2020)

decreased cell number | larval stage | conditional, with Scer\GAL4^srp.D.cCa

(Tattikota et al., 2020)

female semi-sterile, with Scer\GAL4^{VP16.mat.αTub67C}

(Sopko et al., 2014)

Phenotype Manifest In

embryonic/larval crystal cell | decreased number | larval stage, with Scer\GAL4^srp.D.cCa

(Tattikota et al., 2020)

hemocyte | decreased number | larval stage | conditional, with Scer\GAL4^srp.D.cCa

(Tattikota et al., 2020)

lamellocyte | decreased number | larval stage | conditional, with Scer\GAL4^srp.D.cCa

(Tattikota et al., 2020)

Detailed Description

Statement

Reference

The expression of btl^HMS02656 under the control of Scer\GAL4^srp.D.cCa, under control conditions, leads to a decrease in the number of hml+ crystal cells,. Upon wasp infestation, larvae show a decrease in total number of hemocytes, and a decrease in the number of lamellocytes.

(Tattikota et al., 2020)

Females heterozygous for btl^HMS02656 and Scer\GAL4^{mat.αTub67C.T:Hsim\VP16} crossed to btl^HMS02656 males results in: 87% hatching; non-maternal effect.

(Sopko et al., 2014)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions