FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Grip71120
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General Information
Symbol
Dmel\Grip71120
Species
D. melanogaster
Name
FlyBase ID
FBal0281724
Feature type
allele
Associated gene
Dmel\Grip71
Associated Insertion(s)
Carried in Construct
Also Known As
Dgp71WD120
Key Links
Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Reschen et al., 2012)
Mutagen
P-element activity
(Reschen et al., 2012)
Progenitor genotype
P{EP}Grip71GE30807
(Reschen et al., 2012)
Cytology
Description

Imprecise excision of the progenitor insertion, resulting in a deletion that removes the entire Grip71 coding sequence apart from the last 12bp.

(Reschen et al., 2012)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous and hemizygous flies do not show a reduction in lifespan or have any morphological abnormalities.

      Mutant flies do not show uncoordinated behaviour and centriole number in larval neuroblasts is not detectably perturbed.

      Embryos laid by homozygous mothers fail to show any signs of development, although they appear to have been fertilised.

      Meiosis I spindles in mature Grip71120/Df(2L)ED119 oocytes have a significantly reduced spindle area and spindle width compared to wild type, while spindle length and chromosome alignment are unaffected.

      (Reschen et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Grip71120 is rescued by Grip71UAS.cZa/Scer\GAL4ppk.PG

      (Zhang et al., 2024)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Dgp71WD120
      (Romé and Ohkura, 2018, Reschen et al., 2012)
      Grip71120
      grip71120
      (Zhang et al., 2024, Zhu et al., 2023)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)