FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\rpkΔ
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General Information
Symbol
Dmel\rpkΔ
Species
D. melanogaster
Name
FlyBase ID
FBal0281977
Feature type
allele
Associated gene
Dmel\rpk
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Tsubouchi et al., 2012)
Mutagen
FLPase
(Tsubouchi et al., 2012)
Progenitor genotype
PBac{WH}Dlip2f05703
(Tsubouchi et al., 2012)
PBac{WH}f00594
(Tsubouchi et al., 2012)
Caused by aberration
Df(3R)rpk-Karyβ3
Cytology
Description

FLPase-mediated recombination between the two progenitor insertions has resulted in a deletion of the sequence between them, deleting the rpk and Karyβ3 genes.

(Tsubouchi et al., 2012)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3R:4,645,928..4,648,890 [+]
Comment:

Genetically engineered deletion of rpk. Boundaries determined from primer sequences (4 base ambiguity due to repeat at ends).

(Tsubouchi et al., 2012)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Df(3R)rpk-Karyβ3 animals carrying PBac{CH321-22I15.Δrpk} (restoring Karyβ3 but not rpk function) are viable at larval stages, but have somewhat reduced viability at the adult stage.

      Df(3R)rpk-Karyβ3 larvae carrying PBac{CH321-22I15.Δrpk} show a strongly reduced response to gentle touch compared to controls.

      (Tsubouchi et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      rpkΔ
      Name Synonyms
      Secondary FlyBase IDs
        References (1)