FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mtgΔCBD.UAS.EGFP
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General Information
Symbol
Dmel\mtgΔCBD.UAS.EGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0282534
Feature type
allele
Associated gene
Dmel\mtg
Associated Insertion(s)
Carried in Construct
P{UAS-mtg.ΔCBD.GFP}
Key Links
Transgenic product class
inframe_deletion
(Rushton et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Rushton et al., 2012)
Mutagen
in vitro construct
(Rushton et al., 2012)
Progenitor genotype
Carried in construct
P{UAS-mtg.ΔCBD.GFP}
Cytology
Description

UAS regulatory sequences drive expression of mtg which lacks the carbohydrate-binding domain and which is tagged at the C-terminal end with EGFP.

(Rushton et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
mtg
Tagged with
EGFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4da.G32/mtgΔCBD.UAS.EGFP partially rescues mtg1

      (Rushton et al., 2012)
      Comments

      Expression of mtgΔCBD.Scer\UAS.T:Avic\GFP-EGFP under the control of Scer\GAL4da.G32 rescues movement in homozygous mtg1 embryos, although movement is weaker than normal and only a small number of embryos hatch. All larvae die almost immediately, either partially within the egg case, or after crawling and egg-length or two before arrest. Glutamate-gated current amplitudes are restored to wild-type levels at the neuromuscular junctions of rescued embryos.

      (Rushton et al., 2012)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      mtgΔCBD.Scer\UAS.T:Avic\GFP-EGFP
      mtgΔCBD.UAS.EGFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)