FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Spf45UAS.cLa
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General Information
Symbol
Dmel\Spf45UAS.cLa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Lim
FlyBase ID
FBal0283337
Feature type
allele
Associated gene
Dmel\Spf45
Associated Insertion(s)
Carried in Construct
P{UAS-Spf45.L}
Key Links
Transgenic product class
wild_type
(Lim et al., 2008)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Lim et al., 2008)
Mutagen
in vitro construct
(Lim et al., 2008)
Progenitor genotype
Carried in construct
P{UAS-Spf45.L}
Cytology
Description

UAS regulatory sequences drive expression of full length Spf45.

(Lim et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Spf45
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      NOT Enhancer of
      Statement
      Reference

      Spf45UAS.cLa, Scer\GAL4GMR.PF is a non-enhancer of visible | adult stage phenotype of Hsap\ATXN130Q.UAS, Scer\GAL4GMR.PF

      (Lim et al., 2008)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Expression of Spf45Scer\UAS.cLa enhances the ommatidial disorganisation and bristle loss seen when Hsap\ATXN182Q.Scer\UAS is expressed under the control of Scer\GAL4GMR.PF at 25[o]C.

      Expression of Spf45Scer\UAS.cLa has little effect on the mild eye phenotype seen in flies expressing Hsap\ATXN130Q.Scer\UAS under the control of Scer\GAL4GMR.PF at 25[o]C.

      (Lim et al., 2008)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Spf45Scer\UAS.cLa
      Spf45UAS.cLa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Lim
      Secondary FlyBase IDs
        References (1)