FlyBase Allele Report: Hsap\RBM17[UAS.cLa]

General Information

Symbol

Hsap\RBM17^UAS.cLa

Species

H. sapiens

Name

Saccharomyces cerevisiae UAS construct a of Lim

FlyBase ID

FBal0283338

Feature type

allele

Associated gene

Hsap\RBM17

Associated Insertion(s)

Carried in Construct

P{UAS-Hsap\RBM17.L}

Key Links

Transgenic product class

wild_type

(Lim et al., 2008)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Lim et al., 2008)

Mutagen

in vitro construct

(Lim et al., 2008)

Progenitor genotype

Carried in construct

P{UAS-Hsap\RBM17.L}

Cytology

Description

UAS regulatory sequences drive expression of full length Hsap\RBM17.

(Lim et al., 2008)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Hsap\RBM17

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Hsap\RBM17^UAS.cLa, Scer\GAL4^GMR.PF is an enhancer of visible | adult stage phenotype of Hsap\ATXN1^82Q.UAS, Scer\GAL4^GMR.PF

(Lim et al., 2008)

NOT Enhancer of

Statement

Reference

Hsap\RBM17^UAS.cLa, Scer\GAL4^GMR.PF is a non-enhancer of visible | adult stage phenotype of Hsap\ATXN1^30Q.UAS, Scer\GAL4^GMR.PF

(Lim et al., 2008)

Phenotype Manifest In

Enhancer of

Statement

Reference

Hsap\RBM17^UAS.cLa, Scer\GAL4^GMR.PF is an enhancer of eye phenotype of Hsap\ATXN1^82Q.UAS, Scer\GAL4^GMR.PF

(Lim et al., 2008)

Hsap\RBM17^UAS.cLa, Scer\GAL4^GMR.PF is an enhancer of ommatidium phenotype of Hsap\ATXN1^82Q.UAS, Scer\GAL4^GMR.PF

(Lim et al., 2008)

Hsap\RBM17^UAS.cLa, Scer\GAL4^GMR.PF is an enhancer of interommatidial bristle phenotype of Hsap\ATXN1^82Q.UAS, Scer\GAL4^GMR.PF

(Lim et al., 2008)

NOT Enhancer of

Statement

Reference

Hsap\RBM17^UAS.cLa, Scer\GAL4^GMR.PF is a non-enhancer of eye phenotype of Hsap\ATXN1^30Q.UAS, Scer\GAL4^GMR.PF

(Lim et al., 2008)

Hsap\RBM17^UAS.cLa, Scer\GAL4^GMR.PF is a non-enhancer of ommatidium phenotype of Hsap\ATXN1^30Q.UAS, Scer\GAL4^GMR.PF

(Lim et al., 2008)

Hsap\RBM17^UAS.cLa, Scer\GAL4^GMR.PF is a non-enhancer of interommatidial bristle phenotype of Hsap\ATXN1^30Q.UAS, Scer\GAL4^GMR.PF

(Lim et al., 2008)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Expression of Hsap\RBM17^Scer\UAS.cLa enhances the ommatidial disorganisation and bristle loss seen when Hsap\ATXN1^82Q.Scer\UAS is expressed under the control of Scer\GAL4^GMR.PF at 25[o]C.

Expression of Hsap\RBM17^Scer\UAS.cLa has little effect on the mild eye phenotype seen in flies expressing Hsap\ATXN1^30Q.Scer\UAS under the control of Scer\GAL4^GMR.PF at 25[o]C.

(Lim et al., 2008)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Hsap\RBM17^Scer\UAS.cLa

Hsap\RBM17^UAS.cLa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Lim

Secondary FlyBase IDs

References (1)

Report Sections

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