FlyBase Allele Report: Dmel\Mp[UAS.cGa]

General Information

Symbol

Dmel\Mp^UAS.cGa

Species

D. melanogaster

Name

FlyBase ID

FBal0284166

Feature type

allele

Associated gene

Dmel\Mp

Associated Insertion(s)

Carried in Construct

P{UAS-Mp.G}

Key Links

Transgenic product class

wild_type

(Grossman et al., 2011)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Grossman et al., 2011)

Mutagen

in vitro construct

(Grossman et al., 2011)

Progenitor genotype

Carried in construct

P{UAS-Mp.G}

Cytology

Description

UAS regulatory sequences drive expression of Mp coding sequences.

(Grossman et al., 2011)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

adult heart, with Scer\GAL4^tin.cBa

(Grossman et al., 2011)

Detailed Description

Statement

Reference

Expression of mp^Scer\UAS.cGa in the fly heart, under the control of Scer\GAL4^tin.cBa, results in an increase in stress-induced cardiac dysfunction, compared to controls.

Expression of mp^Scer\UAS.cGa in the developing eye under the control of Scer\GAL4^GMR.PF has no effect on eye development.

(Grossman et al., 2011)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhanced by

Statement

Reference

Mp^UAS.cGa, Scer\GAL4^tin.cBa has adult heart phenotype, enhanceable by Hsap\SH3BGR^UAS.cGa, Scer\GAL4^tin.cBa

(Grossman et al., 2011)

NOT Enhanced by

Statement

Reference

Mp^UAS.cGa, Scer\GAL4^tin.cBa has adult heart phenotype, non-enhanceable by Hsap\COL6A2^UAS.cGa, Scer\GAL4^tin.cBa

(Grossman et al., 2011)

Mp^UAS.cGa, Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by Scer\GAL4^tin.cBa/Hsap\COL6A2^UAS.cGa

(Grossman et al., 2011)

Mp^UAS.cGa, Scer\GAL4^tin.cBa has adult heart phenotype, non-enhanceable by Sh3β^UAS.cGa, Scer\GAL4^tin.cBa

(Grossman et al., 2011)

Mp^UAS.cGa, Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by Sh3β^UAS.cGa/Scer\GAL4^tin.cBa

(Grossman et al., 2011)

Mp^UAS.cGa, Scer\GAL4^tin.cBa has adult heart phenotype, non-enhanceable by Mmus\Dscam^UAS.cGa, Scer\GAL4^tin.cBa

(Grossman et al., 2011)

Mp^UAS.cGa, Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by Scer\GAL4^tin.cBa/Hsap\SH3BGR^UAS.cGa

(Grossman et al., 2011)

Mp^UAS.cGa, Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by Scer\GAL4^tin.cBa/Mmus\Dscam^UAS.cGa

(Grossman et al., 2011)

Mp^UAS.cGa, Scer\GAL4^tin.cBa has adult heart phenotype, non-enhanceable by Hsap\COL6A1^UAS.cGa, Scer\GAL4^tin.cBa

(Grossman et al., 2011)

Mp^UAS.cGa, Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by Scer\GAL4^tin.cBa/Hsap\COL6A1^UAS.cGa

(Grossman et al., 2011)

Enhancer of

Statement

Reference

Mp^UAS.cGa, Scer\GAL4^tin.cBa is an enhancer of adult heart phenotype of Hsap\SH3BGR^UAS.cGa, Scer\GAL4^tin.cBa

(Grossman et al., 2011)

NOT Enhancer of

Statement

Reference

Mp^UAS.cGa, Scer\GAL4^tin.cBa is a non-enhancer of adult heart phenotype of Hsap\COL6A2^UAS.cGa, Scer\GAL4^tin.cBa

(Grossman et al., 2011)

Mp^UAS.cGa/Scer\GAL4^tin.cBa is a non-enhancer of eye phenotype of Hsap\COL6A2^UAS.cGa, Scer\GAL4^GMR.PF

(Grossman et al., 2011)

Mp^UAS.cGa, Scer\GAL4^tin.cBa is a non-enhancer of adult heart phenotype of Scer\GAL4^tin.cBa, Sh3β^UAS.cGa

(Grossman et al., 2011)

Mp^UAS.cGa/Scer\GAL4^tin.cBa is a non-enhancer of eye phenotype of Scer\GAL4^GMR.PF, Sh3β^UAS.cGa

(Grossman et al., 2011)

Mp^UAS.cGa/Scer\GAL4^tin.cBa is a non-enhancer of eye phenotype of Hsap\SH3BGR^UAS.cGa, Scer\GAL4^GMR.PF

(Grossman et al., 2011)

Mp^UAS.cGa/Scer\GAL4^tin.cBa is a non-enhancer of eye phenotype of Mmus\Dscam^UAS.cGa, Scer\GAL4^GMR.PF

(Grossman et al., 2011)

Mp^UAS.cGa, Scer\GAL4^tin.cBa is a non-enhancer of adult heart phenotype of Hsap\COL6A1^UAS.cGa, Scer\GAL4^tin.cBa

(Grossman et al., 2011)

Mp^UAS.cGa/Scer\GAL4^tin.cBa is a non-enhancer of eye phenotype of Hsap\COL6A1^UAS.cGa, Scer\GAL4^GMR.PF

(Grossman et al., 2011)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of Sh3β^Scer\UAS.cGa and mp^Scer\UAS.cGa in the fly heart, under the control of Scer\GAL4^tin.cBa does not affect heart function.

Co-expression of mp^Scer\UAS.cGa and Sh3β^Scer\UAS.cGa in the eye under the control of Scer\GAL4^GMR.PF has no effect on eye development.

(Grossman et al., 2011)

Xenogenetic Interactions

Statement

Reference

Co-expression of mp^Scer\UAS.cGa and Hsap\SH3BGR^Scer\UAS.cGa in the fly heart, under the control of Scer\GAL4^tin.cBa, alters heart rate, failure and recovery rate.

Co-expression of Hsap\COL6A1^Scer\UAS.cGa and mp^Scer\UAS.cGa in the fly heart, under the control of Scer\GAL4^tin.cBa, does not affect heart function.

Co-expression of mp^Scer\UAS.cGa and Hsap\COL6A2^Scer\UAS.cGa in the fly heart, under the control of Scer\GAL4^tin.cBa, does not affect heart function.

Co-expression of Mmus\Dscam^Scer\UAS.cGa and mp^Scer\UAS.cGa in the fly heart, under the control of Scer\GAL4^tin.cBa does not affect heart function.

Co-expression of mp^Scer\UAS.cGa and Hsap\COL6A1^Scer\UAS.cGa in the eye under the control of Scer\GAL4^GMR.PF has no effect on eye development.

Co-expression of mp^Scer\UAS.cGa and Hsap\COL6A2^Scer\UAS.cGa in the eye under the control of Scer\GAL4^GMR.PF has no effect on eye development.

Co-expression of mp^Scer\UAS.cGa and Mmus\Dscam^Scer\UAS.cGa in the eye under the control of Scer\GAL4^GMR.PF has no effect on eye development.

Co-expression of mp^Scer\UAS.cGa and Hsap\SH3BGR^Scer\UAS.cGa in the eye under the control of Scer\GAL4^GMR.PF has no effect on eye development.

(Grossman et al., 2011)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Mp^Scer\UAS.cGa

Mp^UAS.cGa

mp^Scer\UAS.cGa

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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