UAS regulatory sequences drive expression of Hsap\SPG20 which is tagged with Tag:MYC.
Scer\GAL4elav-C155/Hsap\SPARTUAS.Tag:MYC is a suppressor of abnormal neuroanatomy | third instar larval stage phenotype of spartin1/Df(3R)110
Scer\GAL4elav-C155/Hsap\SPARTUAS.Tag:MYC is a suppressor of abnormal neuroanatomy | adult stage | progressive phenotype of spartin1/Df(3R)110
Scer\GAL4elav-C155/Hsap\SPARTUAS.Tag:MYC is a suppressor of NMJ bouton | increased number | third instar larval stage phenotype of spartin1/Df(3R)110
Scer\GAL4elav-C155/Hsap\SPARTUAS.Tag:MYC is a suppressor of adult brain | progressive phenotype of spartin1/Df(3R)110
Expression of Hsap\SPG20Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4elav-C155 rescues the increase in bouton number and satellite bouton number seen at the neuromuscular junction in spartin1/Df(3R)110 third instar larvae.
Expression of Hsap\SPG20Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4elav-C155 rescues the show age-dependent neurodegeneration seen in spartin1/Df(3R)110 adults.