FB2026_02 , released June 18, 2026
Allele: Dmel\amxCTLD.MUT
Open Close
General Information
Symbol
Dmel\amxCTLD.MUT
Species
D. melanogaster
Name
FlyBase ID
FBal0284398
Feature type
allele
Associated gene
Dmel\amx
Associated Insertion(s)
Carried in Construct
P{amx.CTLD.MUT}
Key Links
Transgenic product class
missense_variant
(Michellod and Randsholt, 2008)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Michellod and Randsholt, 2008)
Mutagen
in vitro construct
(Michellod and Randsholt, 2008)
Progenitor genotype
Carried in construct
P{amx.CTLD.MUT}
Cytology
Description

A genomic fragment containing a mutant form of amx in which the CTLD signature sequence (LFR) has been changed into RFG by replacing an aliphatic amino acid side chain by a basic one and the basic R side chain by an aliphatic one.

(Michellod and Randsholt, 2008)
Allele components
Component
Use(s)
Regulatory region(s)
amx
Encoded product / tool
amx
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      amxCTLD.MUT rescues amx1

      (Michellod and Randsholt, 2008)
      Comments

      Expression of amxCTLD.MUT rescues the sterility seen in homozygous amx1 mutants.

      (Michellod and Randsholt, 2008)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      amxCTLD.MUT
      Name Synonyms
      Secondary FlyBase IDs
        References (1)